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Invitrogen™ TIM-1 Monoclonal Antibody (12B1C8H3), Invitrogen™
Mouse Monoclonal Antibody
258.00€ - 449.00€
Spécification
| Antigène | TIM-1 |
|---|---|
| Clone | 12B1C8H3 |
| Concentration | 1 mg/mL |
| Applications | ELISA |
| Classification | Monoclonal |
| Code produit | Marque | Quantité | Prix | Quantité et disponibilité | |||||
|---|---|---|---|---|---|---|---|---|---|
| Code produit | Marque | Quantité | Prix | Quantité et disponibilité | |||||
|
17719743
|
Invitrogen™
MA543383 |
50 μL |
258.00€
50µL |
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|
17799563
|
Invitrogen™
MA543014 |
100 μL |
449.00€
100µL |
Veuillez vous connecter pour pouvoir commander cet article. Besoin d'un compte web? Créer le vôtre dès maintenant! | |||||
Description
Specificity: Human HAVCR1/TIM1/KIM1
CD365 also known as T-cell immunoglobulin and mucin domain 1 (Tim-1) is a type 1 surface glycoprotein that consists of extracellular N-terminal immunoglobulin V-like domain and a mucin domain, and a short cytoplasmic tail. The endogenous ligand for CD365 is Tim-4. In addition, CD365 is known to be a cellular receptor or co-receptor for a number of viruses including hepatitis A and C viruses, Ebola virus, Marburg virus, Dengue virus, Zika virus, West Nile virus, and Japanese encephalitis virus. The direct binding of the viruses by CD365 occurs via phosphatildyl-serine exposed on viral envelopes. Polymorphisms within human CD365 gene (HAVCR1) are associated with susceptibility to infection and the disease severity. CD365 has also been implicated in the T cell co-stimulation. CD365 is primarily expressed in epithelial cells. It is also highly expressed in A549, 769-P and Caco-2 and cell lines. CD365 exists also as a soluble protein generated by metalloproteinase mediated proteolytic cleavage of the surface protein.Spécification
| TIM-1 | |
| 1 mg/mL | |
| Monoclonal | |
| Liquid | |
| RUO | |
| PBS with no preservative | |
| AI503787; CD365; HAVCR; HAVCR1; HAVcr-1; Hepatitis A virus cellular receptor 1; hepatitis A virus cellular receptor 1 homolog; Kidney injury molecule 1; Kim1; KIM-1; T cell immunoglobin domain and mucin domain protein 1; t cell immunoglobulin and mucin domain-containing protein 1; T cell membrane protein 1; T-cell immunoglobulin and mucin domain containing 1; T-cell immunoglobulin and mucin domain-containing protein 1; T-cell immunoglobulin mucin family member 1; T-cell immunoglobulin mucin receptor 1; T-cell membrane protein 1; TIM; TIM1; TIM-1; TIMD1; TIMD-1 | |
| Havcr1 | |
| IgG1 | |
| Protein A | |
| Antibody |
| 12B1C8H3 | |
| ELISA | |
| Unconjugated | |
| Mouse | |
| Human | |
| Q96D42 | |
| 26762 | |
| Recombinant Human HAVCR1 protein. | |
| Primary | |
| -20°C, Avoid Freeze/Thaw Cycles | |
| Havcr1 |
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