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Invitrogen™ TRPA1 Polyclonal Antibody, DyLight™ 650
Rabbit Polyclonal Antibody
Marca: Invitrogen™ PA522832
Les retours ne sont pas autorisés pour ce produit.
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Descrizione
The target sequence has 69% sequence homology with rat. Suggested positive control: human brain membrane fraction.
TRPA1 is a TRP-related channel that responds to cold temperatures and pungent compounds and plays a role in both nociceptor and hair cell transduction. TRPA1 is a transformation -associated gene product in lung epithelia, whereas its protein distribution is primarily restricted to sensory neurons. Blocking TRPA1 may be a therapeutic target for treating cold hyperalgesia caused by inflammation and nerve damage. It is now known that TRPA1 protein is also widely expressed outside of the CNS and is dys-regulated during oncogenic transformation. The structure of TRPA1 is highly related to both the protein ankyrin and transmembrane proteins. The specific function of TRPA1 has not yet been determined; however, studies indicate the function may involve a role in signal transduction and growth control.
Specifica
| TRPA1 | |
| Polyclonal | |
| DyLight 650 | |
| Trpa1 | |
| Anktm1; ankyrin-like with transmembrane domains 1; ankyrin-like with transmembrane domains protein 1; FEPS; ion channel; drTRPA1; nompC; transformation-sensitive protein p120; transient receptor potential A1; transient receptor potential ankyrin 1a; transient receptor potential cation channel subfamily A member 1; transient receptor potential cation channel subfamily A member 1a; transient receptor potential cation channel, subfamily A, member 1a; transient receptor potential cation channel subfamily A member 1-like; transient receptor potential cation channel, subfamily A, member 1; transient receptor potential cation channel, subfamily A, member 1 L homeolog; transient receptor potential cation channel, subfamily A, member 1a; TRPA1; TRPA-1; trpa1.L; trpa1a; TRPA1b; XELAEV_18003616mg | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 100526649, 277328, 312896, 474351, 8989 | |
| 4°C, store in dark | |
| Liquid |
| ELISA, Flow Cytometry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry | |
| 0.63 mg/mL | |
| 50mM sodium borate with 0.05% sodium azide | |
| O75762, Q6RI86, Q8BLA8 | |
| Trpa1, trpa1a | |
| A synthetic peptide made to a region within the N-terminus (residues 1-100) of the human TRPA1 protein. | |
| 100 μL | |
| Primary | |
| Human, Mouse, Rat, Guinea Pig, Zebrafish | |
| Antibody | |
| IgG |
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