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Invitrogen™ YPEL3 Polyclonal Antibody
Rabbit Polyclonal Antibody
Marque: Invitrogen™ PA556490
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Description
Immunogen sequence: MVRISKPKTF QAYLDDCHRR YSCAHCRAHL ANHDDLISKS FQGSQGRAYL FNSVVNVGCG PAEERVLLTG LHAVADIHCE NCKTTLGWKY EQAFESSQK Highest antigen sequence identity to the following orthologs: Mouse - 100%, Rat - 100%.
YPEL3 (yippee-like 3) belongs to a family of five yippee-like proteins, all of which localize to the centrosome or mitotic spindle and are widely expressed in both adult and fetal tissue. This localization plus the fact that the family of human YPEL proteins share a high degree of sequence homology across species suggests that these proteins may have a conserved function involved in cell division. YPEL3 is a p53-regulated gene whose expression is induced by DNA damage and in turn induces cellular senescence. It appears to function as a tumor suppressor as it is downregulated in colon and breast tumors.
Spécification
| YPEL3 | |
| Polyclonal | |
| Unconjugated | |
| YPEL3 | |
| 0610043B10Rik; 1190001G19Rik; FKSG5; Protein yippee-like 3; RGD1564579; small ubiquitinated apoptotic protein; Suap; yippee like 3; yippee-like 3; yippee-like 3 (Drosophila); YPEL3 | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 83719 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
| Immunohistochemistry (Paraffin) | |
| 0.1 mg/mL | |
| PBS with 40% glycerol and 0.02% sodium azide; pH 7.2 | |
| P61236 | |
| YPEL3 | |
| Recombinant protein corresponding to Human YPEL3. Recombinant protein control fragment (Product #RP-101075). | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
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