missing translation for 'onlineSavingsMsg'
Learn More

AIPL1 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Marque:  Proteintech 15108-1-AP-20UL

Informations supplémentaires : Poids : 0.00010kg

 Afficher plus de versions de ce produit

Code produit. 16834134

  • 121.38€ / 20µL
Expédition estimée: 28-09-2022
pour voir le stock disponible 

Veuillez vous pour pouvoir commander cet article. Besoin d'un compte web? Créer le vôtre dès maintenant!


Description

Description

Aipl1 was initially identified as a protein implicated in Leber congenital amaurosis (LCA), an autosomal recessive disorder thought to be caused by the abnormal development of photoreceptors. Aipl1 is a tetratricopeptide repeat protein that is highly homologous to ARA9, a protein involved in the HSP90-mediated nuclear translocation and transactivation of the aryl hydrocarbon receptor. Aipl1 has also been found to function as part of a chaperone heterocomplex, interacting with Hsp90 and Hsp70. Aipl1 also associates with the cell cycle regulator NUB1. It is thought that Aipl1 cooperates with Hsp70 but not Hsp90 to suppress the formation of NUB1 inclusions, and these interactions are necessary in the normal photoreceptor maturation, as mutations that lead to LCA also compromise the interactions with the Hsp chaperones. At least three isoforms of Aipl1 are known to exist.
Spécification

Spécification

AIPL1
Polyclonal
Unconjugated
AIPL1
AIPL1, AIPL2, LCA4
Rabbit
Antigen Affinity Chromatography
RUO
114230, 23746, 59110
-20°C
Liquid
Western Blot, Immunoprecipitation, Immunohistochemistry (Paraffin)
0.21 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Q924K1, Q9JLG9, Q9NZN9
Aipl1
AIPL1 Fusion Protein Ag4625
20 μL
Primary
Human, Rat, Mouse
Antibody
IgG
Vidéos
FDS
Documents
Certificats
Promotions

Promotions