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CD90.1 Mouse, PE, Clone: OX-7, BD
Mouse Monoclonal Antibody
Marque: BD Biosciences 554898
Informations supplémentaires : Poids : 0.01000kg
Description
CD90 (Thy-1) is a GPI-anchored membrane glycoprotein of the Ig superfamily which is involved in signal transduction. The OX-7 clone reacts with rat CD90 reported to be expressed by hematopoietic stem cells, early myeloid & erythroid cells, immature B lymphocytes in the bone marrow & peripheral lymphoid organs, thymocytes, recent thymic emigrants (a subset of CD45RC- peripheral T lymphocytes), neurons, glomerular mesangial cells, endothelium at inflammatory sites, mast cells, and dendritic cells. Rat dendritic epidermal T cells (DEC) have been reported to be CD90 (Thy-1) negative, unlike those of the mouse. The OX-7 clone has been reported to crossreact with the mouse CD90.1 (Thy-1.1) alloantigen of the AKR/J and PL strains, but not CD90.2 (Thy-1.2) found on many mouse strains. In the mouse, CD90 is found on thymocytes, most peripheral T lymphocytes, some intraepithelial T lymphocytes (IEL, DEC), hematopoietic stem cells, and neurons, but not B lymphocytes. In addition, there is evidence that CD90 mediates adhesion of mouse thymocytes to mouse thymic stroma. The OX-7 clone has also been reported to crossreact with rabbit and guinea pig thymus, brain, and intestine.
Flow Cytometry
Spécification
| CD90.1 | |
| Monoclonal | |
| 0.2mg/mL | |
| Rat Thy-1; Mouse Thy-1.1 | |
| Mouse | |
| Affinity Purified | |
| RUO | |
| Primary | |
| Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. |
| Flow Cytometry | |
| OX-7 | |
| PE | |
| Aqueous buffered solution containing ≤0.09% sodium azide. | |
| Rat thymocyte Thy-1 antigen | |
| 0.2 mg | |
| Immunology | |
| Guinea Pig, Mouse, Rabbit, Rat | |
| IgG1 κ |
For Research Use Only.