missing translation for 'onlineSavingsMsg'
Learn More

HAX-1 Mouse, Unlabeled, Clone: 52, BD

Mouse Monoclonal Antibody

Marque:  BD Biosciences 610824

Informations supplémentaires : Poids : 0.01000kg

 Afficher plus de versions de ce produit

Code produit. 15875659

  • 330.00€ / 1 kit
Expédition estimée: 22-04-2024
pour voir le stock disponible 

Veuillez vous pour pouvoir commander cet article. Besoin d'un compte web? Créer le vôtre dès maintenant!


Description

Description

Cell-cell interactions in the immune system, mediated by membrane-bound antigen receptors, trigger a cascade of signaling mechanisms collectively known as the T-cell response. Upon antigen binding, cellular tyrosine kinases are activated resulting in the phosphorylation of HS1 or Lck-binding protein 1 (LckBP1), which is involved in thymic negative selection. HS1 is one of the earliest intracellular proteins to be tyrosine phosphorylated in response to antigen-receptor cross-linking in T cells. HAX-1 (HS1-associated protein X-1) is a 35kDa protein found associated with HS1 by co-immunoprecipitation assays and the two-hybrid system. HAX-1 is ubiquitously expressed and localized in the mitochondria, endoplasmic reticulum, and the nuclear envelope. The HS1-HAX-1 complex may be critical for signal transduction pathways initiated by antigen presentation to T cells.

Immunofluorescence, Immunoprecipitation, Western Blotting

Spécification

Spécification

HAX-1
Monoclonal
250μg/mL
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Human HAX-1 aa. 10-148
50 μg
Cell Biology
Human, Mouse, Rat
IgG1
Western Blot
52
Unconjugated
Mouse
Affinity Purified
RUO
Primary
Store undiluted at -20°C.
Suggestions de produits

Suggestions de produits

Vidéos
FDS
Documents

Documents

Certificats
Promotions

Promotions

For Research Use Only.