missing translation for 'onlineSavingsMsg'
Learn More

JNK/SAPK (pT183/pY185) Mouse, Unlabeled, Clone: 41, BD

Mouse Monoclonal Antibody

420.00€ - 780.00€

Spécification

Antigène JNK/SAPK (pT183/pY185)
Clone 41
Concentration 250μg/mL
Applications Western Blot
Classification Monoclonal
Consulter d'autres spécifications

Produits 2
Code produit Marque Quantité Prix Quantité et disponibilité  
Code produit Marque Quantité Prix Quantité et disponibilité  
15866209
Afficher les documents Détails de la promotion
BD Biosciences
612540
50 μg
420.00€
1 pièce
Voir les produits de remplacement
Économisez jusqu'à 
»
Expédition estimée: 23-04-2024
pour voir le stock disponible 
Veuillez vous pour pouvoir commander cet article. Besoin d'un compte web? Créer le vôtre dès maintenant!
15876209
Afficher les documents Détails de la promotion
BD Biosciences
612541
150 μg
780.00€
1 pièce
Voir les produits de remplacement
Économisez jusqu'à 
»
Expédition estimée: 23-04-2024
pour voir le stock disponible 
Veuillez vous pour pouvoir commander cet article. Besoin d'un compte web? Créer le vôtre dès maintenant!
Description

Description

The Ras signaling pathway links the signals from growth factor receptors with the activation of the MAPK kinase cascade of phosphorylation leading to cell growth and differentiation. External stimuli, like endotoxins, UV irradiation, heat, and hyperosmolarity, induce an array of cellular responses that culminate with gene expression, ultimately dictating an adaptation to the new environment. Small GTPases of the Rho family, including cdc42, Rac1, and Rho, transmit the stress signals that initiate the signal cascade. JNK is a c-Jun kinase that was also identified as SAPK1 and MAPKp49. JNK/SAPK, along with p38 and RK5/BMK1, comprise three classes of stress-activated MAPK groups. Complete activation of JNK/SAPK requires the phosphorylation of both Thr183 and Tyr185, which are located in a Thr-X-Tyr motif. The activation of these residues is believed to be carried out by MKK4 and MKK7. Active JNK/SAPK phosphorylates other kinases and multiple transcription factors that induce expression of genes, such as proinflammatory cytokines.

Flow Cytometry, Western Blotting

Spécification

Spécification

JNK/SAPK (pT183/pY185)
250μg/mL
Monoclonal
Mouse
Cell Biology
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
IgG1
Affinity Purified
41
Western Blot
Unconjugated
RUO
Human, Mouse, Rat
Phosphorylated Human JNK/SAPK (pT183/pY185) Peptide
Primary
Store undiluted at -20°C.
Vidéos
FDS
Documents

Documents

Product Certifications

For Research Use Only.