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Neurotensin Receptor 3 (NTR3) Mouse, Unlabeled, Clone: 48, BD

Mouse Monoclonal Antibody

330.00€ - 650.00€

Spécification

Antigène Neurotensin Receptor 3 (NTR3)
Clone 48
Concentration 250μg/mL
Applications Western Blot
Classification Monoclonal
Consulter d'autres spécifications

Produits 2
Code produit Marque Quantité Prix Quantité et disponibilité  
Code produit Marque Quantité Prix Quantité et disponibilité  
15876089
Afficher les documents Détails de la promotion
BD Biosciences
612100
50 μg
330.00€
1 kit
Voir les produits de remplacement
Économisez jusqu'à 
»
Expédition estimée: 23-04-2024
pour voir le stock disponible 
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15886089
Afficher les documents Détails de la promotion
BD Biosciences
612101
150 μg
650.00€
1 kit
Voir les produits de remplacement
Économisez jusqu'à 
»
Expédition estimée: 23-04-2024
pour voir le stock disponible 
Veuillez vous pour pouvoir commander cet article. Besoin d'un compte web? Créer le vôtre dès maintenant!
Description

Description

Neurotensin (NT) is a neuropeptide that modulates dopaminergic transmission, triggers analgesic responses, induces hypotension, decreases gastric acid secretion, and activates lipid digestion. NT is a ligand for NT receptors, which include both G-protein coupled and non-G-protein coupled receptors. Neurotensin Receptor 3 (NTR3) is a non-G-protein coupled receptor that has a lumenal domain homologous to sorting proteins, and a short cytoplasmic tail homologous to mannose-6-phosphate/IGF-II receptor. NTR3 was also identified as sortilin/gp95, a component of GLUT4 vesicles in adipocytes that has been implicated in lipoprotein lipase degradation. NTR3 mRNA is expressed in brain, skeletal muscle, heart, and adipocytes. NTR3 mature protein has 44 N-terminal amino acid residues cleaved off, which may facilitate ligand binding to the receptor. Cellular localization of NTR3 is in the Golgi compartment and vesicles, as well as on the cell surface. In addition to roles in neuropeptide and lipoprotein degradation, NTR3 may also be involved in receptor protein sorting. Thus, NTR3 is a multifunctional transmembrane protein that acts as both a intracellular sorting receptor and extracellular ligand-binding receptor.

Immunofluorescence, Western Blotting

Spécification

Spécification

Neurotensin Receptor 3 (NTR3)
250μg/mL
Monoclonal
Mouse
Cell Biology
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
IgG1
Affinity Purified
NTR3
48
Western Blot
Unconjugated
RUO
Canine, Chicken, Human, Mouse, Rat
Human Neurotensin Receptor 3 aa. 300-422
Primary
Store undiluted at -20°C.
Vidéos
FDS
Documents

Documents

Product Certifications

For Research Use Only.