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ARHGAP24 Rabbit anti-Canine, Human, Mouse, Rat, Zebrafish, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Marque:  Proteintech 18834-1-AP-150UL

Informations supplémentaires : Poids : 0.00010kg

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Code produit. 16828684

  • 325.38€ / 150µL
Expédition estimée: 28-09-2022
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Description

Description

The antibody may recognize all the isoforms of ARHGAP24 except isoform 5.

Rho GTPase-activating protein involved in cell polarity, cell morphology and cytoskeletal organization. Acts as a GTPase activator for the Rac-type GTPase by converting it to an inactive GDP-bound state. Controls actin remodeling by inactivating Rac downstream of Rho leading to suppress leading edge protrusion and promotes cell retraction to achieve cellular polarity. Able to suppress RAC1 and CDC42 activity in vitro. Overexpression induces cell rounding with partial or complete disruption of actin stress fibers and formation of membrane ruffles, lamellipodia, and filopodia. Isoform 2 is a vascular cell-specific GAP involved in modulation of angiogenesis.
Spécification

Spécification

ARHGAP24
Polyclonal
Unconjugated
ARHGAP24
ARHGAP24, Filamin A associated RhoGAP, FILGAP, p73, p73RhoGAP, RC GAP72, RCGAP72, Rho type GTPase activating protein 24, RhoGAP of 73 kDa, Sarcoma antigen NY SAR 88
Rabbit
Antigen Affinity Chromatography
RUO
100005116, 231532, 305156, 478463, 83478
-20°C
Liquid
Western Blot, Immunohistochemistry (Paraffin)
0.31 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Q5U2Z7, Q8C4V1, Q8N264
ARHGAP24
Peptide
150 μL
Primary
Zebrafish, Rat, Mouse, Human, Canine
Antibody
IgG
Vidéos
FDS
Documents
Certificats
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