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ATG5 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
140.00€ - 399.00€
Spécification
Antigène | ATG5 |
---|---|
Concentration | 0.27 mg/mL |
Applications | Immunocytochemistry, Immunohistochemistry (Paraffin), Immunofluorescence, Western Blot |
Classification | Polyclonal |
Conjugué | Unconjugated |
Code produit | Marque | Quantité | Prix | Quantité et disponibilité | |||||
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Code produit | Marque | Quantité | Prix | Quantité et disponibilité | |||||
16846393
|
Proteintech
10181-2-AP-20UL |
20 μL |
140.00€
20µL |
Expédition estimée: 06-05-2024 Connectez-vous pour voir le stock disponible |
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16836393
|
Proteintech
10181-2-AP-150UL |
150 μL |
399.00€
150µL |
Expédition estimée: 23-04-2024 Connectez-vous pour voir le stock disponible |
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Description
This antibody is raised against 28-275 amino acids of human ATG5. It can recognize the ATG5-ATG12 complex (55 kDa) which can be truncated and generate a 40-45 kDa band. 10181-2-AP also recognizes the free ATG5 (32 kDa).
Macroautophagy is the major inducible pathway for the general turnover of cytoplasmic constituents in eukaryotic cells, it is also responsible for the degradation of active cytoplasmic enzymes and organelles during nutrient starvation. Macroautophagy involves the formation of double-membrane bound autophagosomes which enclose the cytoplasmic constituent targeted for degradation in a membrane bound structure, which then fuse with the lysosome (or vacuole) releasing a single-membrane bound autophagic bodies which are then degraded within the lysosome (or vacuole). APG5, required for autophagy, conjugates to ATG12 and associates with an isolation membrane to form a cup-shaped isolation membrane and autophagosome. The conjugate detaches from the membrane immediately before or after autophagosome formation is completed. APG5 may also play an important role in the apoptotic process, possibly within the modified cytoskeleton. Its expression is a relatively late event in the apoptotic process, occurring downstream of caspase activity.Spécification
ATG5 | |
Immunocytochemistry, Immunohistochemistry (Paraffin), Immunofluorescence, Western Blot | |
Unconjugated | |
Rabbit | |
Human, Mouse, Rat | |
Q3MQ06, Q99J83, Q9H1Y0 | |
11793, 365601, 9474 | |
ATG5 Fusion Protein Ag0214 | |
Primary | |
-20°C | |
ATG5 |
0.27 mg/mL | |
Polyclonal | |
Liquid | |
RUO | |
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3 | |
APG5, APG5 LIKE, APG5L, Apoptosis specific protein, ASP, ATG5, Autophagy protein 5, hAPG5 | |
Atg5 | |
IgG | |
Antigen Affinity Chromatography | |
Antibody |