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BAX Mouse anti-Human, Mouse, Rat, Clone: 4G5E8, Proteintech

Mouse Monoclonal Antibody

Marque:  Proteintech 60267-1-IG-20UL

Informations supplémentaires : Poids : 0.00010kg

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Code produit. 16827325

  • 121.38€ / 20µL
Expédition estimée: 10-10-2022
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Description

Description

BAX is a members of the Bcl-2 Family and plays an important role in regulation of apoptosis. Whereas Bcl-2 is commonly regarded as an anti-apoptotic protein, BAX is considered to have a pro-apoptotic function. Regulation of apoptosis is supposed to involve both homo- and heterodimerization of different isoforms of BAX and Bcl-2. The Bax gene encodes different isoforms including Bax alpha (21 kDa) and Bax beta (24 kDa), whereas both isoforms contain the BH1, BH2 and BH3 domains, Bax beta has a unique carboxyl terminus and does not contain a hydrophobic transmembrane domain. Bcl-2 is also expressed in different Isoforms. Bcl-2 beta differs in the 3′ UTR and coding region compared to variant alpha. Bcl-2 beta is shorter (22 kDa) and has a distinct C-terminus compared to Bcl-2 alpha (26 kDa).BAX is a member of the BCL-2 family of proteins, which function as regulators of apoptosis. Overexpression of BAX functions to promote cell death. BAX can form homodimers and is also able to heterodimerize with other BCL-2 related proteins.
Spécification

Spécification

BAX
Monoclonal
1.6 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Q07812, Q07813, Q63690
Bax
BAX Fusion Protein Ag21068
20 μL
Primary
Mouse, Human, Rat
Antibody
IgG2b
Immunocytochemistry, Western Blot, Immunohistochemistry (Paraffin), Immunofluorescence
4G5E8
Unconjugated
BAX
Apoptosis regulator BAX, BAX
Mouse
Protein A
RUO
12028, 24887, 581
-20°C
Liquid
Vidéos
FDS
Documents
Certificats
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