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Bestrophin-1 Rabbit anti-Human, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Marque:  Proteintech 21910-1-AP-20UL

Informations supplémentaires : Poids : 0.00010kg

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Code produit. 16891455

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Description

Description

This gene encodes a member of the bestrophin gene family. This small gene family is characterized by proteins with a highly conserved N-terminus with four to six transmembrane domains. Bestrophins may form chloride ion channels or may regulate voltage-gated L-type calcium-ion channels. Bestrophins are generally believed to form calcium-activated chloride-ion channels in epithelial cells but they have also been shown to be highly permeable to bicarbonate ion transport in retinal tissue. Mutations in this gene are responsible for juvenile-onset vitelliform macular dystrophy (VMD2), also known as Best macular dystrophy, in addition to adult-onset vitelliform macular dystrophy (AVMD) and other retinopathies. Alternative splicing results in multiple variants encoding distinct isoforms.
Spécification

Spécification

Bestrophin-1
Polyclonal
Unconjugated
BEST1
ARB, BEST, BEST1, bestrophin 1, Bestrophin-1, BMD, TU15B, VMD2
Rabbit
Antigen Affinity Chromatography
RUO
7439
-20°C
Liquid
Western Blot
0.51 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
O76090
BEST1
Bestrophin-1 Fusion Protein Ag15129
20 μL
Primary
Human
Antibody
IgG
Vidéos
FDS
Documents

Documents

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