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BLVRA Rabbit anti-Human, Mouse, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Marque:  Proteintech 10775-1-AP-150UL

Informations supplémentaires : Poids : 0.00010kg

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Code produit. 16827383

  • 325.38€ / 150µL
Expédition estimée: 30-09-2022
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Description

Description

Biliverdin reductase (BLVR) is a ubiquitously expressed, small cytoplasmic oxidoreductase that catalyzes the reduction of biliverdin to bilirubin. The first step of this process is catalyzed by heme oxygenase, an enzyme that converts heme to iron, carbon monoxide, and biliverdin. BLVR is unique among all enzymes to date in being dual pH/dual cofactor-dependent, as it requires NADH (pH 6. 7) or NADPH (pH 8. 7) as an electron donor. There are two isoforms of BLVR, biliverdin-IX alpha-reductase (BLVRA), the major component of human adult liver, and biliverdin-IX beta-reductase (BLVRB), found predomitly in fetal liver. The product of BLVR, bilirubin, is an important biological antioxidant, however it is also a neurotoxin and the cause of kernicterus. In addition to being an antioxidant, it inhibits kinase activity and the activity of enzymes such as protein kinase C and NADPH oxidase.
Spécification

Spécification

BLVRA
Polyclonal
Unconjugated
BLVRA
Biliverdin IX alpha reductase, biliverdin reductase A, BLVR, BLVRA, BVR, BVR A, BVRA
Rabbit
Antigen Affinity Chromatography
RUO
109778, 644
-20°C
Liquid
Western Blot, Immunohistochemistry (Paraffin), Immunofluorescence, Immunocytochemistry
0.43 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
P53004, Q9CY64
BLVRA
BLVRA Fusion Protein Ag1166
150 μL
Primary
Mouse, Human
Antibody
IgG
Vidéos
FDS
Documents
Certificats
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