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BRCA2 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Marque:  Proteintech 19791-1-AP-150UL

Informations supplémentaires : Poids : 0.00010kg

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Code produit. 16829274

  • 325.38€ / 150µL
Expédition estimée: 28-09-2022
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Description

Description

Inherited mutations in BRCA1 and this gene, BRCA2, confer increased lifetime risk of developing breast or ovarian cancer. Both BRCA1 and BRCA2 are involved in maintece of genome stability, specifically the homologous recombination pathway for double-strand DNA repair. The BRCA2 protein contains several copies of a 70 aa motif called the BRC motif, and these motifs mediate binding to the RAD51 recombinase which functions in DNA repair. BRCA2 is considered a tumor suppressor gene, as tumors with BRCA2 mutations generally exhibit loss of heterozygosity (LOH) of the wild-type allele.
Spécification

Spécification

BRCA2
Polyclonal
Unconjugated
BRCA2
BRCA2, BRCC2, breast cancer 2, early onset, BROVCA2, FACD, FAD, FAD1, FANCB, FANCD, FANCD1
Rabbit
Antigen Affinity Chromatography
RUO
12190, 360254, 675
-20°C
Liquid
Western Blot, Immunohistochemistry (Paraffin)
0.13 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
O35923, P51587, P97929
Brca2
Peptide
150 μL
Primary
Rat, Mouse, Human
Antibody
IgG
Vidéos
FDS
Documents
Certificats
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