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C4-B alpha chain/C4b-B/C4d-B Rabbit anti-Human, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
140.00€ - 399.00€
Spécification
Antigène | C4-B alpha chain/C4b-B/C4d-B |
---|---|
Concentration | 0.4 mg/mL |
Applications | Western Blot |
Classification | Polyclonal |
Conjugué | Unconjugated |
Code produit | Marque | Quantité | Prix | Quantité et disponibilité | |||||
---|---|---|---|---|---|---|---|---|---|
Code produit | Marque | Quantité | Prix | Quantité et disponibilité | |||||
16806725
|
Proteintech
55228-1-AP-20UL |
20 μL |
140.00€
20µL |
Expédition estimée: 03-05-2024 Connectez-vous pour voir le stock disponible |
Veuillez vous connecter pour pouvoir commander cet article. Besoin d'un compte web? Créer le vôtre dès maintenant! | ||||
16896715
|
Proteintech
55228-1-AP-150UL |
150 μL |
399.00€
150µL |
Expédition estimée: 03-05-2024 Connectez-vous pour voir le stock disponible |
Veuillez vous connecter pour pouvoir commander cet article. Besoin d'un compte web? Créer le vôtre dès maintenant! | ||||
Description
This antibody raised against 1116-1128aa of human C4-B protein can recognize C4-B precursor, C4-B alpha chain, C4b-B, and C4d-B.
This gene encodes the basic form of complement factor 4, part of the classical activation pathway. The protein is expressed as a single chain precursor which is proteolytically cleaved into a trimer of alpha, beta, and gamma chains prior to secretion. The trimer provides a surface for interaction between the antigen-antibody complex and other complement components. The alpha chain may be cleaved to release C4 anaphylatoxin, a mediator of local inflammation. Deficiency of this protein is associated with systemic lupus erythematosus. This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. Varying haplotypes of this gene cluster exist, such that individuals may have 1, 2, or 3 copies of this gene. In addition, this gene exists as a long form and a short form due to the presence or absence of a 6.4 kb endogenous HERV-K retrovirus in intron 9.Spécification
C4-B alpha chain/C4b-B/C4d-B | |
Western Blot | |
Unconjugated | |
Rabbit | |
Human | |
P0C0L5 | |
721 | |
Peptide | |
Primary | |
-20°C | |
C4B |
0.4 mg/mL | |
Polyclonal | |
Liquid | |
RUO | |
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 | |
C4, C4B, C4B1, C4B12, C4B2, C4B3, C4B5, C4F, CH, CO4, Complement C4-B, CPAMD3 | |
C4B | |
IgG | |
Antigen Affinity Chromatography | |
Antibody |