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Cathepsin F Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Marque:  Proteintech 11055-1-AP-20UL

Informations supplémentaires : Poids : 0.00010kg

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Code produit. 16827873

  • 121.38€ / 20µL
Expédition estimée: 06-10-2022
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Description

Description

Cathepsins are papain family cysteine proteinases that represent a major component of the lysosomal proteolytic system. Cathepsins generally contain a signal sequence, followed by a propeptide and then a catalytically active mature region. The very long (251 amino acid residues) proregion of the cathepsin F precursor contains a C-terminal domain similar to the pro-segment of cathepsin L-like enzymes, a 50-residue flexible linker peptide, and an N-terminal domain predicted to adopt a cystatin-like fold. The cathepsin F proregion is unique within the papain family cysteine proteases in that it contains this additional N-terminal segment predicted to share structural similarities with cysteine protease inhibitors of the cystatin superfamily. This cystatin-like domain contains some of the elements known to be important for inhibitory activity. CTSF encodes a predicted protein of 484 amino acids which contains a 19 residue signal peptide. Cathepsin F contains five potential N-glycosylation sites, and it may be targeted to the endosomal/lysosomal compartment via the mannose 6-phosphate receptor pathway. The cathepsin F gene is ubiquitously expressed, and it maps to chromosome 11q13, close to the gene encoding cathepsin W.
Spécification

Spécification

Cathepsin F
Polyclonal
Unconjugated
CTSF
Cathepsin F, CATSF, CTSF
Rabbit
Antigen Affinity Chromatography
RUO
361704, 56464, 8722
-20°C
Liquid
Western Blot, Immunohistochemistry (Paraffin)
0.25 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Q9R013, Q9UBX1
Ctsf
Cathepsin F Fusion Protein Ag1521
20 μL
Primary
Mouse, Rat, Human
Antibody
IgG
Vidéos
FDS
Documents
Certificats
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