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CD11b Rat anti-Mouse, FITC, Clone: M1/70, BD
Rat Monoclonal Antibody
118.00€ - 459.00€
Spécification
Antigène | CD11b |
---|---|
Clone | M1/70 |
Concentration | 0.5mg/mL |
Applications | Flow Cytometry |
Classification | Monoclonal |
Code produit | Marque | Quantité | Prix | Quantité et disponibilité | |||||
---|---|---|---|---|---|---|---|---|---|
Code produit | Marque | Quantité | Prix | Quantité et disponibilité | |||||
15831239
|
BD Biosciences
561688 |
25 μg |
118.00€
1 pièce |
Expédition estimée: 10-06-2024 Connectez-vous pour voir le stock disponible |
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15828908
|
BD Biosciences
557396 |
0.1 mg |
223.00€
1 pièce |
Expédition estimée: 10-06-2024 Connectez-vous pour voir le stock disponible |
Veuillez vous connecter pour pouvoir commander cet article. Besoin d'un compte web? Créer le vôtre dès maintenant! | ||||
15867138
|
BD Biosciences
553310 |
0.5 mg |
459.00€
1 pièce |
Expédition estimée: 10-06-2024 Connectez-vous pour voir le stock disponible |
Veuillez vous connecter pour pouvoir commander cet article. Besoin d'un compte web? Créer le vôtre dès maintenant! | ||||
Description
The M1/70 monoclonal antibody specifically binds to CD11b, also known as Integrin alpha M (Itgam or αM). CD11b is a 170-kDa type 1 transmembrane glycoprotein and belongs to the Integrin alpha chain family. CD11b serves as the alpha chain of the heterodimeric Mac-1 integrin (CD11b/CD18, αMβ2), also known as complement receptor 3 (CR3). Mac-1 mediates adhesion to ICAM-1 (CD54), ICAM-2 (CD102), fibrinogen and binding to C3bi. Mac-1 is expressed at varying levels on granulocytes, macrophages, myeloid-derived dendritic cells, natural killer cells, microglia, and B-1 B lymphocytes. Mac-1 expression is rapidly up-regulated on neutrophils after activation, in the same time period that CD62L (L-selectin) is shed from the cell surface. The M1/70 antibody reportedly blocks cell adherence and C3bi binding but does not block cell-mediated lysis. Cross-reaction of the M1/70 antibody with CD11b expressed on human monocytes, polymorphonuclear leukocytes, and NK cells has been reported.
Spécification
CD11b | |
0.5mg/mL | |
Monoclonal | |
Rat | |
Human, Mouse | |
IgG2b κ | |
Affinity Purified | |
Itgam; Integrin alpha-M; Ly-40; Mac-1a; Mac-1 alpha; CR3A; CR-3 alpha chain |
M1/70 | |
Flow Cytometry | |
FITC | |
RUO | |
Aqueous buffered solution containing ≤0.09% sodium azide. | |
Primary | |
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. |
For Research Use Only.