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CD14 Mouse anti-Human, Mouse, Clone: 2C1D9, Proteintech

Mouse Monoclonal Antibody

Marque:  Proteintech 60253-1-IG-150UL

Informations supplémentaires : Poids : 0.00010kg

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Code produit. 16837295

  • 325.38€ / 150µL
Expédition estimée: 10-10-2022
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Description

Description

CD14 is a 55 kDa GPI-anchored glycoprotein that is constitutively expressed on the surface of mature monocytes, macrophages, and neutrophils. CD14 also serves as a multifunctional lipopolysaccharide receptor, and is released to the serum both as a secreted and enzymatically cleaved GPI-anchored form. CD14 binds lipopolysaccharide molecule in a reaction catalyzed by lipopolysaccharide-binding protein (LBP), an acute phase serum protein. The soluble sCD14 can discriminate slight structural differences between lipopolysaccharides and is important for neutralization of serum allochthonous lipopolysaccharides by reconstituted lipoprotein particles. Further, CD14 has been shown to bind apoptotic cells, and can affect allergic, inflammatory and infectious processes. Alternative splicing results in multiple transcript variants encoding the same CD14 isoform. Diseases associated with CD14 dysfunction include mycobacterium chelonae infection and Croup.
Spécification

Spécification

CD14
Monoclonal
0.5 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
P08571, P10810
CD14
CD14 Fusion Protein Ag10693
150 μL
Primary
Mouse, Human
Antibody
IgG1
Western Blot, Immunohistochemistry (Paraffin), Immunofluorescence, Immunocytochemistry
2C1D9
Unconjugated
CD14
CD14, CD14 molecule
Mouse
Protein G
RUO
12475, 929
-20°C
Liquid
Vidéos
FDS
Documents
Certificats
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