Learn More
CD142 Monoclonal Antibody (HTF-1), Functional Grade, eBioscience™, Invitrogen™
Mouse Monoclonal Antibody
Marque: Affymetrix eBioscience 16-1429-025
Description
This HTF-1 MAb reacts with human CD142, which is also known as Tissue Factor. Expression of this type I transmembrane glycoprotein on endothelial cells, monocytes, macrophages, and platelets can be induced by inflammatory mediators (e.g., LPS, IL-1b, TNFa, PMA, or endotoxin). On the other hand, CD142 is expressed constitutively by some tumor cells (e.g., lung, pancreatic, breast, and colon) and non-immune tissues such as the vasculature, central nervous system, kidney, epithelia, and placenta. Studies have also suggested that CD142 exists as a soluble form that circulates in blood. CD142 initiates blood coagulation by associating with and activating the circulating factors VII and VIIa. The HTF-1 antibody has been reported to exhibit blocking activity.
CD142 Monoclonal antibody specifically detects CD142 in Human samples. It is validated for Flow Cytometry, Functional Assay, Immunocytochemistry, Immunofluorescence, Western Blot
Spécification
| CD142 | |
| Monoclonal | |
| 1 mg/mL | |
| PBS with no preservative; pH 7.2 | |
| P13726 | |
| Mouse | |
| 25 mg | |
| Primary | |
| Human | |
| Antibody | |
| IgG1 κ |
| Flow Cytometry, Functional Assay, Immunocytochemistry, Immunofluorescence, Western Blot | |
| HTF-1 | |
| Functional Grade | |
| F3 | |
| AA409063; CD142; Cf3; Cf-3; Coagulation factor III; coagulation factor III (thromboplastin, tissue factor); coagulation factor III, tissue factor; F3; TF; TFA; Thromboplastin; Tissue factor | |
| Affinity chromatography | |
| RUO | |
| 2152 | |
| 4° C | |
| Liquid |
Veuillez fournir vos retours sur le contenu du produit en remplissant le formulaire ci-dessous.