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  6. CD142 Monoclonal Antibody (HTF-1), Functional Grade, eBioscience™, Invitrogen™
  7. 17101152

CD142 Monoclonal Antibody (HTF-1), Functional Grade, eBioscience™, Invitrogen™

Mouse Monoclonal Antibody

Marque:  Affymetrix eBioscience 16-1429-025

Code nomenclature Nacres: NA.46

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Code produit. 17101152

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Description

Description

This HTF-1 MAb reacts with human CD142, which is also known as Tissue Factor. Expression of this type I transmembrane glycoprotein on endothelial cells, monocytes, macrophages, and platelets can be induced by inflammatory mediators (e.g., LPS, IL-1b, TNFa, PMA, or endotoxin). On the other hand, CD142 is expressed constitutively by some tumor cells (e.g., lung, pancreatic, breast, and colon) and non-immune tissues such as the vasculature, central nervous system, kidney, epithelia, and placenta. Studies have also suggested that CD142 exists as a soluble form that circulates in blood. CD142 initiates blood coagulation by associating with and activating the circulating factors VII and VIIa. The HTF-1 antibody has been reported to exhibit blocking activity.

CD142 Monoclonal antibody specifically detects CD142 in Human samples. It is validated for Flow Cytometry, Functional Assay, Immunocytochemistry, Immunofluorescence, Western Blot
TRUSTED_SUSTAINABILITY
Spécification

Spécification

CD142
Monoclonal
1 mg/mL
PBS with no preservative; pH 7.2
P13726
Mouse
25 mg
Primary
Human
Antibody
IgG1 κ
Flow Cytometry, Functional Assay, Immunocytochemistry, Immunofluorescence, Western Blot
HTF-1
Functional Grade
F3
AA409063; CD142; Cf3; Cf-3; Coagulation factor III; coagulation factor III (thromboplastin, tissue factor); coagulation factor III, tissue factor; F3; TF; TFA; Thromboplastin; Tissue factor
Affinity chromatography
RUO
2152
4° C
Liquid
Produktförslag

Produktförslag

Filmer
SDS
Dokument

Dokument

Produktspecifikationer
Kampanjer

Kampanjer

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