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CD16 Monoclonal Antibody (3G8), NovaFluor™ Yellow 610, eBioscience™, Invitrogen™

Mouse Monoclonal Antibody

163.00€ - 361.00€

Spécification

Antigène CD16
Clone 3G8
Concentration 4 μL/Test
Applications Flow Cytometry
Classification Monoclonal
Consulter d'autres spécifications

Produits 2
Code produit Marque Quantité Prix Quantité et disponibilité  
Code produit Marque Quantité Prix Quantité et disponibilité  
17206526
Afficher les documents Détails de la promotion
Invitrogen
H006T02Y03
25 Tests
163.00€
25 tests
Voir les produits de remplacement
Économisez jusqu'à 
»
Expédition estimée: 19-04-2024
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17256536
Afficher les documents Détails de la promotion
Invitrogen
H006T03Y03
100 Tests
361.00€
100 tests
Voir les produits de remplacement
Économisez jusqu'à 
»
Expédition estimée: 19-04-2024
pour voir le stock disponible 
Veuillez vous pour pouvoir commander cet article. Besoin d'un compte web? Créer le vôtre dès maintenant!
Description

Description

This 3G8 monoclonal ab reacts with human and Non-human Primate CD16,also known aslow-affinity Fc gamma RIII. CD16 exists as two distinct isoforms, Fc gamma RIIIA and Fc gamma RIIIB. In humans, Fc gamma RIIIA is expressed as a polypeptide-anchored form on monocytes, macrophages, and lymphocytes such as NK cells. T and B cells do not express this Fc receptor. Fc gamma RIIIB is also detected on neutrophils as a GPI-anchored form. Expression of CD16 on lymphocytes and monocytes is similar in Non-human Primates. However, while CD16 is not found on neutrophils in macaques and baboons, this receptor is detected on these cells in sooty mangabeys. Binding of IgG leads to activation of signal transduction pathways, resulting in ab-dependent cell-mediated cytotoxicity(ADCC), phagocytosis, cytokine release, and antigen presentation.
Based on cross-blocking studies 3G8 recognizes the same epitope as CB16. However, 3G8 and B73.1 ab clones bind distinct epitopes.
Applications Reported: This 3G8 ab has been reported for use in flow cytometric analysis.
Applications Tested: This 3G8 ab has been pre-diluted and tested by flow cytometric analysis of normal human peripheral blood cells. This may be used at 4uL(0.6ug) per test. A test is defined as the amount(ug) of ab that will stain a cell sample in a final volume of 100uL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test.
Excitation: 552 nm; Emission: 612 nm; Laser: 561 nm(Yellow) Laser

CD16 Monoclonal antibody specifically detects CD16 in Baboon, Chimpanzee, Cynomolgus Monkey, Human, Non-human Primate, Rhesus Monkey samples. It is validated for Flow Cytometry.
Spécification

Spécification

CD16
4 μL/Test
Monoclonal
Liquid
RUO
PBS with 0.09% sodium azide; pH 7.2
4833442P21Rik; CD16; CD16-2; CD16A; CD16a antigen; CD16b; CD32; CD32 receptor 2; CDw32; cytolytic trigger molecule G7; Fc fragment of IgG intermediate affinity IV receptor; Fc fragment of IgG low affinity IIIa receptor; Fc fragment of IgG receptor IIIa; Fc fragment of IgG receptor IIIb; Fc fragment of IgG, low affinity III, receptor for (CD16); Fc fragment of IgG, low affinity IIIa, receptor; Fc fragment of IgG, low affinity IIIa, receptor (CD16a); Fc fragment of IgG, low affinity IIIa, receptor for (CD16); Fc fragment of IgG, low affinity IIIa, receptor for (CD16); Fc fragment of IgG, low affinity III, receptor for (CD16); Fc fragment of IgG, low affinity IIIb, receptor (CD16b); Fc gamma receptor III; Fc gamma receptor IIIa; Fc gamma receptor III-A; Fc gamma receptor IIIb; Fc gamma RIIIa; Fc gammaRIV; Fc receptor, IgG, low affinity III; Fc receptor, IgG, low affinity IV; Fc receptor-like 3; Fcg receptor III; FCG2; FCG3; Fc-gamma receptor III-2 (CD 16); Fc-gamma receptor IIIb (CD 16);
Fcgr3, FCGR3A, FCGR3B
Primary
4° C, store in dark, DO NOT FREEZE!
FCGR3A
3G8
Flow Cytometry
NovaFluor Yellow 610
Mouse
Baboon, Chimpanzee, Cynomolgus Monkey, Human, Non-human Primate, Rhesus Monkey
A3RFZ7, O75015, P08637
2214, 2215, 720006
IgG1
Affinity chromatography
Antibody
Vidéos
FDS
Documents

Documents

Product Certifications