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CD69 Hamster anti-Mouse, PE, Clone: H1.2F3, BD
Hamster Monoclonal Antibody
Marca: BD Biosciences 555318
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Descrizione
The In-1 monoclonal antibody specifically binds to CD74, the MHC class II-associated Invariant chain (Ii), expressed in I-A+ cell populations. Although it is predominantly expressed intracellularly, it has also been detected on the cell surface of some B-cell lines and at low levels on a small number of B lymphocytes. In the mouse, alternatively spliced transcripts encode 31-kDa and 41-kDa isoforms, and the cell-surface CD74 has a chondroitin sulfate side chain which allows it to interact with CD44. CD74 is directly involved in the intracellular transport of MHC class II molecules and antigen presentation, and it affects the maturation of T and B lymphocytes.
Specifica
| CD74 | |
| Monoclonal | |
| 0.5mg/mL | |
| Cd74; CLIP; Ii; Ia-associated invariant chain; Ia-GAMMA; DHLAG; HG2A; HLADG | |
| Rat | |
| Affinity Purified | |
| RUO | |
| Primary | |
| Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. |
| Flow Cytometry | |
| IN-1 | |
| FITC | |
| Aqueous buffered solution containing ≤0.09% sodium azide. | |
| ATL mouse lymphocytes and B10A mouse-derived CH1 B-cell lymphoma | |
| 0.5 mg | |
| Immunology | |
| Mouse | |
| IgG2b κ |
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