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Cofilin Polyclonal Antibody, Invitrogen™
Rabbit Polyclonal Antibody
Marque: Invitrogen PA524628
Code nomenclature Nacres: NA.41
Informations supplémentaires : Poids : 0.01000kg
Description
This antibody is predicted to react with bovine, chicken, porcine, non-human primate, rat and Xenopus based on sequence homology.
Cofilin binds to F-actin and exhibits pH-sensitive F-actin depolymerizing activity. Regulates actin cytoskeleton dynamics. Important for normal progress through mitosis and normal cytokinesis. Plays a role in the regulation of cell morphology and cytoskeletal organization. Required for the up-regulation of atypical chemokine receptor ACKR2 from endosomal compartment to cell membrane, increasing its efficiency in chemokine uptake and degradation. Required for neural tube morphogenesis and neural crest cell migration.Spécification
| Cofilin | |
| Polyclonal | |
| Unconjugated | |
| CFL1 | |
| 18 kDa phosphoprotein; AA959946; CFL; Cfl1; CFL-1; Cof; COF1; cofilin; cofilin 1; cofilin 1 (non-muscle); cofilin 1, non-muscle; cofilin, non-muscle isoform; Cofilin1; Cofilin-1; cofilin-1-like protein; epididymis secretory protein Li 15; HEL-S-15; n-cofilin; p18 | |
| Rabbit | |
| Antigen affinity chromatography, Protein A | |
| RUO | |
| 1072, 12631 | |
| -20° C, Avoid Freeze/Thaw Cycles | |
| Liquid |
| Flow Cytometry, Western Blot | |
| 0.25 mg/mL | |
| PBS with 0.09% sodium azide | |
| P18760, P23528 | |
| CFL1 | |
| KLH conjugated synthetic peptide between 70-98 amino acids from the central region of human CFL1 | |
| 400 μL | |
| Primary | |
| Human, Mouse | |
| Antibody | |
| IgG |