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DCUN1D5 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Marque:  Proteintech 14810-1-AP-150UL

Informations supplémentaires : Poids : 0.00010kg

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Code produit. 16833644

  • 325.38€ / 150µL
Expédition estimée: 30-09-2022
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Description

Description

Conjugation of Nedd8 to a cullin protein, termed neddylation, is an evolutionarily conserved process that functions to activate the cullin-RING family E3 ubiquitin ligases, leading to increased proteasomal degradation of a wide range of substrate proteins. Cellular neddylation requires the action of DCN1 (Defective in cullin neddylation protein 1), which, in humans, consists of five homologues designated as DCNL1-5. DCUN1D5 gene encodes the 28 kDa DCUN1 domain-containing protein 5 containing a C-terminal potentiating neddylation domain. The cellular function of DCUN1D5 needs to be explored, recently, a mono-ubiquitination-mediated mechanism that governs nuclear-cytoplasmic trafficking of hDCNL1, was reported to regulate hDCNL1-dependent activation of the cullin-RING E3 ubiquitin ligases in selected cellular compartments.
Spécification

Spécification

DCUN1D5
Polyclonal
Unconjugated
DCUN1D5
DCN1 like protein 5, DCUN1D5
Rabbit
Antigen Affinity Chromatography
RUO
315405, 76863, 84259
-20°C
Liquid
Western Blot, Immunoprecipitation, Immunofluorescence, Immunocytochemistry
0.29 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Q5PPL2, Q9BTE7, Q9CXV9
Dcun1d5
DCUN1D5 Fusion Protein Ag6534
150 μL
Primary
Rat, Mouse, Human
Antibody
IgG
Vidéos
FDS
Documents
Certificats
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