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GMPS Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Marque:  Proteintech 16376-1-AP-150UL

Informations supplémentaires : Poids : 0.00010kg

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Code produit. 16895974

  • 349.00€ / 150µL
Expédition estimée: 09-12-2022
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Description

Description

Transcription factor which plays a key role in defining the composition of the RNA polymerase II (RNAPII) elongation complex and in modulating the production of mature mRNA transcripts. Acts as an assembly factor to recruit various factors to the RNAPII elongation complex and is recruited to the complex via binding to the transcription elongation factor SUPT6H bound to the C-terminal domain (CTD) of the RNAPII subunit RPB1 (POLR2A). The SUPT6H:IWS1:CTD complex recruits mRNA export factors (ALYREF/THOC4, EXOSC10) as well as histone modifying enzymes (such as SETD2) to ensure proper mRNA splicing, efficient mRNA export and elongation-coupled H3K36 methylation, a signature chromatin mark of active transcription.
Spécification

Spécification

GMPS
Polyclonal
Unconjugated
GMPS
Glutamine amidotransferase, GMP synthetase, GMPS
Rabbit
Antigen Affinity Chromatography
RUO
229363, 295088, 8833
-20°C
Liquid
Western Blot, Immunoprecipitation, Immunohistochemistry (Paraffin)
0.34 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
P49915, Q3THK7, Q4V7C6
Gmps
GMPS Fusion Protein Ag9350
150 μL
Primary
Rat, Mouse, Human
Antibody
IgG
Vidéos
FDS
Documents
Certificats
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