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HERC5 Rabbit anti-Human, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Marque:  Proteintech 22692-1-AP-150UL

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Code produit. 16802055

  • 399.00€ / 150µL

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Description

Description

HERC5 is a probable E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. This gene is a member of the HERC family of ubiquitin ligases and encodes a protein with a HECT domain and five RCC1 repeats. Pro-inflammatory cytokines upregulate expression of this gene in endothelial cells. The protein localizes to the cytoplasm and perinuclear region and functions as an interferon-induced E3 protein ligase that mediates ISGylation of protein targets. The gene lies in a cluster of HERC family genes on chromosome 4.
Spécification

Spécification

HERC5
Polyclonal
Unconjugated
HERC5
CEB1, CEBP1, Cyclin E binding protein 1, E3 ISG15 protein ligase HERC5, hect domain and RLD 5, HERC5
Rabbit
Antigen Affinity Chromatography
RUO
51191
-20°C
Liquid
Immunohistochemistry (Paraffin), Immunoprecipitation
0.21 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Q9UII4
HERC5
HERC5 Fusion Protein Ag18449
150 μL
Primary
Human
Antibody
IgG
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