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HERC5 Rabbit anti-Human, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Marque: Proteintech 22692-1-AP-150UL
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Description
HERC5 is a probable E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. This gene is a member of the HERC family of ubiquitin ligases and encodes a protein with a HECT domain and five RCC1 repeats. Pro-inflammatory cytokines upregulate expression of this gene in endothelial cells. The protein localizes to the cytoplasm and perinuclear region and functions as an interferon-induced E3 protein ligase that mediates ISGylation of protein targets. The gene lies in a cluster of HERC family genes on chromosome 4.Spécification
HERC5 | |
Polyclonal | |
Unconjugated | |
HERC5 | |
CEB1, CEBP1, Cyclin E binding protein 1, E3 ISG15 protein ligase HERC5, hect domain and RLD 5, HERC5 | |
Rabbit | |
Antigen Affinity Chromatography | |
RUO | |
51191 | |
-20°C | |
Liquid |
Immunohistochemistry (Paraffin), Immunoprecipitation | |
0.21 mg/mL | |
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 | |
Q9UII4 | |
HERC5 | |
HERC5 Fusion Protein Ag18449 | |
150 μL | |
Primary | |
Human | |
Antibody | |
IgG |