IL-13 Rat anti-Mouse, Alexa Fluor® 488, Clone: eBio13A, eBioscience™
Rat Monoclonal Antibody
Marque: Affymetrix eBioscience 53-7133-80
Code nomenclature Nacres: NA.41
Informations supplémentaires : Poids : 0.25000kg
DescriptionIL-13 is an immunoregulatory cytokine produced primarily by activated Th2 cells, and is involved in regulating inflammatory and immune responses. IL-13 down-regulates macrophage activity, thereby inhibiting the production of pro-inflammatory cytokines and chemokines, and is involved in allergen-induced asthma through mechanisms independent of IgE and eosinophils. IL-13 also regulates several stages of B cell maturation and differentiation, up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching of B cells. Structurally, IL-13 closely resembles IL-3, IL-4, IL-5 and GM-CSF. The gene encoding IL-13, IL3, IL5, IL4, and CSF2 form a cytokine gene cluster on chromosome 5q, with the IL-13 gene particularly close to IL4.
|PBS with 0.1% gelatin and 0.09% sodium azide; pH 7.2|
|Interleukin-13, ALRH antibody, NC30 antibody, P600 antibody|
|Alexa Fluor™ 488|
|4° C, store in dark, DO NOT FREEZE!|
For Research Use Only.