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IL-2 Polyclonal Antibody, PeproTech®, Invitrogen™

Rabbit Polyclonal Antibody

Marque:  Invitrogen 500-P111-50UG

Code nomenclature Nacres: NA.41

Informations supplémentaires : Poids : 0.16500kg

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Code produit. 17894333

  • 204.00€ / 50µg
Expédition estimée: 12-08-2024
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Description

Description

AA Sequence of recombinant protein: PTSSSTSSST AEAQQQQQQQ QQQQQHLEQL LMDLQELLSR MENYRNLKLP RMLTFKFYLP KQATELKDLQ CLEDELGPLR HVLDLTQSKS FQLEDAENFI SNIRVTVVKL KGSDNTFECQ FDDESATVVD FLRRWIAFCQ SIISTSPQ. Preparation: Produced from sera of rabbits immunized with highly pure Recombinant Murine IL-2. Anti-Murine IL-2-specific antibody was purified by affinity chromatography employing an immobilized Murine IL-2 matrix. Sandwich ELISA: To detect Murine IL-2 by sandwich ELISA (using 100 μL/well antibody solution) a concentration of 0.5-2.0 μg/mL of this antibody is required. This antigen affinity purified antibody, in conjunction with PeproTech Biotinylated Anti-Murine IL-2 (500-P111Bt) as a detection antibody, allows the detection of at least 0.2-0.4 ng/well of Recombinant Murine IL-2. Western Blot: To detect Murine IL-2 by Western Blot analysis this antibody can be used at a concentration of 0.1-0.2 μg/mL. Used in conjunction with compatible secondary reagents the detection limit for Recombinant Murine IL-2 is 1.5-3.0 ng/lane, under either reducing or non-reducing conditions.

Interleukin 2 (IL-2) is an immuno-modulatory cytokine that is important for the proliferation of activated T cells, differentiation of B cells, natural killer cells, monocytes and macrophages. IL-2 signals through the IL-2 receptor (IL-2R), a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL-4) and interleukin 7 (IL-7). The expression of the IL-2 gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a gene similar to IL-2 in mice leads to an μgcerative colitis-like disease that suggests an essential role of this gene in the immune response to antigenic stimuli.
Spécification

Spécification

IL-2
Polyclonal
Unconjugated
IL2
aldesleukin; cytokine; H-IL-2; il 2; Il2; Il-2; ILN; Interleukin; interleukin 2; interleukin 2 precursor; interleukin 2 variant IL2delta2; Interleukin2; Interleukin-2; interleukin-2 precursor; interleukin-2 precursor protein; interleukin-2; interleukin 2; Involved in regulation of T cell clonal expansion; involved in regulation of T-cell clonal expansion; lymphokine; M-IL-2; patial sequence of Interleukin-2; POIL2; porcine Interleukin 2; T cell growth factor; T-cell growth factor; T-cell growth factor (TCGF); TCGF
Rabbit
Antigen affinity chromatography
RUO
16183
-20°C
ELISA, Western Blot
0.1-1.0 mg/mL
PBS with no preservative
P04351
IL2
E.coli-derived Recombinant Murine IL-2
50μg
Primary
Mouse
Lyophilized
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