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IQGAP3 Rabbit anti-Human, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Marque:  Proteintech 25930-1-AP-20UL

Informations supplémentaires : Poids : 0.00010kg

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Code produit. 16804475

  • 112.71€ / 20µL

Expédition estimée
26-04-2021

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Description

Description

IQGAP3 (IQ motif containing GTPase activating protein 3) is a 1, 631 amino acid protein that acts as an effector of Cdc42 and Rac 1, linking their activation to the cytoskeleton during neuronal morphogenesis. A novel member of the IQGAP family, IQGAP3 is highly expressed in brain where it localizes to axons of hippocampal neurons. IQGAP3 contains one Ras-GAP domain, a CH (calponin-homology) domain, four IQ domains and is encoded by a gene located on human chromosome 1, which spans 260 million base pairs, contains over 3, 000 genes and comprises nearly 8% of the human genome. Chromosome 1 houses a large number of disease-associated genes, including those that are involved in familial adenomatous polyposis, Stickler syndrome, Parkinson′s disease, Gaucher disease, schizophrenia and Usher syndrome. Aberrations in chromosome 1 are found in a variety of cancers, including head and neck cancer, maligt melanoma and multiple myeloma.
Spécification

Spécification

IQGAP3
0.25 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Q86VI3
IQGAP3
Rabbit
IgG
20 μL
-20°C
Primary
128239
Western Blot, Immunohistochemistry (Paraffin)
Unconjugated
IQGAP3
Liquid
IQGAP3
IQGAP3 Fusion Protein Ag23109
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Human
Vidéos
FDS
Documents