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IRF7 Rabbit anti-Human, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Marque:  Proteintech 22392-1-AP-20UL

Informations supplémentaires : Poids : 0.00010kg

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Code produit. 16831915

  • 121.38€ / 20µL
Expédition estimée: 03-10-2022
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Description

Description

This antibody is a rabbit polyclonal antibody raised against the C-terminal 349 amino acid residues of human IRF7 D. The molecular weight of non-phosphorylated IRF7 is 44 kDa while phosphorylated IRF7 is 80-90 kDa.

Interferons (IFNs) are involved in a multitude of immune interactions during viral infections and play a major role in both the induction and regulation of innate and adaptive antiviral mechanisms. During infection, host-virus interactions signal downstream molecules such as transcription factors such as IFN regulatory factor-3 (IRF3) which can act to stimulate transcription of IFN-a/b genes. IRF7 has been shown to play a role in the transcriptional activation of virus-inducible cellular genes, including interferon beta chain genes. IRF7 play a major role in the innate immune pathway, interacting with the Toll-like receptor (TLR) adaptor proteins MyD88 and Tirp/TRAM and functioning as an intermediate TLR4 and TLR9 signaling. There are at least four differentially spliced isoforms of IRF7, although their function has not been clearly established.
Spécification

Spécification

IRF7
Polyclonal
Unconjugated
IRF7
interferon regulatory factor 7, IRF 7, IRF 7H, IRF7, IRF7A
Rabbit
Antigen Affinity Chromatography
RUO
3665
-20°C
Liquid
Immunoprecipitation, Immunohistochemistry (Paraffin), Western Blot
0.35 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Q92985
IRF7
IRF7 Fusion Protein Ag18059
20 μL
Primary
Human
Antibody
IgG
Vidéos
FDS
Documents
Certificats
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