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IRSp53 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Marque:  Proteintech 11087-2-AP-20UL

Informations supplémentaires : Poids : 0.00010kg

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Code produit. 16827933

  • 121.38€ / 20µL
Expédition estimée: 06-10-2022
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Description

Description

The protein encoded by this gene has been identified as a brain-specific angiogenesis inhibitor (BAI1)-binding protein. This adaptor protein links membrane bound G-proteins to cytoplasmic effector proteins. This protein functions as an insulin receptor tyrosine kinase substrate and suggests a role for insulin in the central nervous system. It also associates with a downstream effector of Rho small G proteins, which is associated with the formation of stress fibers and cytokinesis. This protein is involved in lamellipodia and filopodia formation in motile cells and may affect neuronal growth-cone guidance. This protein has also been identified as interacting with the dentatorubral-pallidoluysian atrophy gene, which is associated with an autosomal domit neurodegenerative disease. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
Spécification

Spécification

IRSp53
Polyclonal
Unconjugated
BAIAP2
BAI associated protein 2, BAI1 associated protein 2, BAIAP2, BAP2, Fas ligand associated factor 3, FLAF3, Insulin receptor substrate p53, IRS 58, IRSp53, IRSp53/58, Protein BAP2
Rabbit
Antigen Affinity Chromatography
RUO
10458, 108100, 117542
-20°C
Liquid
Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
0.4 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Q6GMN2, Q8BKX1, Q9UQB8
BAIAP2
IRSp53 Fusion Protein Ag1552
20 μL
Primary
Mouse, Rat, Human
Antibody
IgG
Vidéos
FDS
Documents
Certificats
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