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CD36/GPIIIb/GPIV Ab-3 Mouse Monoclonal Antibody, Epredia™
Ensure accurate, reproducible results in immunohistochemistry , immunofluorescence, flow cytometry and function blocking experiment.
Marque: Epredia MS-756-PABX
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Description
CD36 (also known as platelet glycoprotein IV, OKM5-antigen, or platelet glycoprotein IIIb) acts as a receptor for thrombospondin (TSP), collagen, falciparum malaria parasitized erythrocytes, and sickle erythrocytes. It also functions as a scavenger receptor, mediating macrophage uptake of oxidized low-density lipoprotein (LDL), and apoptotic polymorphonuclear leukocytes (PMN). CD36 plays a role in platelet aggregation, macrophage foam cell development, inflammation, and the tissue ischaemia observed in sickle cell disease and cerebral malaria. Ab-3 blocks adhesion of P. falciparum parasitized red blood cells to CD36 and strongly inhibits collagen-induced platelet aggregation.Host Species: Mouse
Clone: 185-1G2
Isotype: IgG2a/κ
Species Reactivity: Human. Others not tested.
Epitope: Not determined
Immunogen: Stimulated human leukocytes
Molecular Weight: 88 kDa
Positive Control: Tonsil
Cellular Localization: Membrane
Recommended for:
- Immunohistochemistry (Frozen only)
- Western Blotting (Not suitable)
- Immunofluorescence
- Flow Cytometry
- Function Blocking
Note:
USA: RUO; Int'l: RUO
Spécification
| CD36/GPIIIb/GPIV Ab-3 | |
| Monoclonal | |
| 1mg/mL | |
| Mouse | |
| 200 μL | |
| Hematopoietic | |
| Human | |
| IgG2a κ |
| Flow Cytometry, Immunofluorescence, Immunohistochemistry (Frozen) | |
| 185-1G2 | |
| Unconjugated | |
| Stimulated human leukocytes | |
| RUO | |
| Primary | |
| Concentrated |
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