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MMS19 Mouse anti-Human, Mouse, Rat, Clone: 2H6D8, Proteintech
Mouse Monoclonal Antibody
140.00€ - 399.00€
Spécification
Antigène | MMS19 |
---|---|
Clone | 2H6D8 |
Concentration | 0.98 mg/mL |
Applications | Western Blot, Immunoprecipitation, Immunohistochemistry (Paraffin), Immunocytochemistry, Immunofluorescence |
Classification | Monoclonal |
Code produit | Marque | Quantité | Prix | Quantité et disponibilité | |||||
---|---|---|---|---|---|---|---|---|---|
Code produit | Marque | Quantité | Prix | Quantité et disponibilité | |||||
16847575
|
Proteintech
66049-1-IG-20UL |
20 μL |
140.00€
20µL |
Expédition estimée: 27-05-2024 Connectez-vous pour voir le stock disponible |
Veuillez vous connecter pour pouvoir commander cet article. Besoin d'un compte web? Créer le vôtre dès maintenant! | ||||
16837575
|
Proteintech
66049-1-IG-150UL |
150 μL |
399.00€
150µL |
Expédition estimée: 27-05-2024 Connectez-vous pour voir le stock disponible |
Veuillez vous connecter pour pouvoir commander cet article. Besoin d'un compte web? Créer le vôtre dès maintenant! | ||||
Description
Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into apoproteins specifically involved in DNA metabolism and genomic integrity. In the CIA complex, MMS19 acts as an adapter between early-acting CIA components and a subset of cellular target iron-sulfur proteins such as ERCC2/XPD, FANCJ and RTEL1, thereby playing a key role in nucleotide excision repair (NER) and RNA polymerase II (POL II) transcription. As part of the mitotic spindle-associated MMXD complex, plays a role in chromosome segregation, probably by facilitating iron-sulfur cluster assembly into ERCC2/XPD. Indirectly acts as a transcriptional coactivator of estrogen receptor (ER), via its role in iron-sulfur insertion into some component of the TFIIH-machinery.Spécification
MMS19 | |
0.98 mg/mL | |
Monoclonal | |
Liquid | |
RUO | |
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 | |
hMMS19, MET18, MET18 homolog, MMS19, MMS19 like protein, MMS19L | |
Mms19 | |
IgG2b | |
Protein A | |
Antibody |
2H6D8 | |
Western Blot, Immunoprecipitation, Immunohistochemistry (Paraffin), Immunocytochemistry, Immunofluorescence | |
Unconjugated | |
Mouse | |
Human, Rat, Mouse | |
Q96T76, Q9D071 | |
171124, 64210, 72199 | |
MMS19 Fusion Protein Ag8960 | |
Primary | |
-20°C | |
MMS19 |