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MMS19 Mouse anti-Human, Mouse, Rat, Clone: 2H6D8, Proteintech

Mouse Monoclonal Antibody

Marque:  Proteintech 66049-1-IG-150UL

Informations supplémentaires : Poids : 0.00010kg

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Code produit. 16837575

  • 325.38€ / 150µL
Expédition estimée: 30-09-2022
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Description

Description

Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into apoproteins specifically involved in DNA metabolism and genomic integrity. In the CIA complex, MMS19 acts as an adapter between early-acting CIA components and a subset of cellular target iron-sulfur proteins such as ERCC2/XPD, FANCJ and RTEL1, thereby playing a key role in nucleotide excision repair (NER) and RNA polymerase II (POL II) transcription. As part of the mitotic spindle-associated MMXD complex, plays a role in chromosome segregation, probably by facilitating iron-sulfur cluster assembly into ERCC2/XPD. Indirectly acts as a transcriptional coactivator of estrogen receptor (ER), via its role in iron-sulfur insertion into some component of the TFIIH-machinery.
Spécification

Spécification

MMS19
Monoclonal
0.98 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Q96T76, Q9D071
Mms19
MMS19 Fusion Protein Ag8960
150 μL
Primary
Rat, Mouse, Human
Antibody
IgG2b
Western Blot, Immunoprecipitation, Immunohistochemistry (Paraffin), Immunofluorescence, Immunocytochemistry
2H6D8
Unconjugated
MMS19
hMMS19, MET18, MET18 homolog, MMS19, MMS19 like protein, MMS19L
Mouse
Protein A
RUO
171124, 64210, 72199
-20°C
Liquid
Vidéos
FDS
Documents
Certificats
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