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MPP8 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Marque:  Proteintech 16796-1-AP-20UL

Informations supplémentaires : Poids : 0.00010kg

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Code produit. 16896534

  • 129.00€ / 20µL
Expédition estimée: 19-12-2022
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Description

Description

Heterochromatin component that specifically recognizes and binds methylated ′Lys-9′ of histone H3 (H3K9me) and promotes recruitment of proteins that mediate epigenetic repression. Mediates recruitment of the HUSH complex to H3K9me3 sites: the HUSH complex is recruited to genomic loci rich in H3K9me3 and is probably required to maintain transcriptional silencing by promoting recruitment of SETDB1, a histone methyltransferase that mediates further deposition of H3K9me3. Binds H3K9me and promotes DNA methylation by recruiting DNMT3A to target CpG sites; these can be situated within the coding region of the gene. Mediates down-regulation of CDH1 expression.
Spécification

Spécification

MPP8
Polyclonal
Unconjugated
MPHOSPH8
HSMPP8, M phase phosphoprotein 8, MPHOSPH8, MPP8, TWA3
Rabbit
Antigen Affinity Chromatography
RUO
290270, 54737, 75339
-20°C
Liquid
Immunoprecipitation, Western Blot
0.31 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
G3V8T1, Q3TYA6, Q99549
Mphosph8
MPP8 Fusion Protein Ag10268
20 μL
Primary
Human, Rat, Mouse
Antibody
IgG
Vidéos
FDS
Documents

Documents

Certificats
Promotions

Promotions