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NDUFAF2 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Marque:  Proteintech 13891-1-AP-20UL

Informations supplémentaires : Poids : 0.00010kg

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Code produit. 16832304

  • 121.38€ / 20µL
Expédition estimée: 28-09-2022
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Description

Description

Mimitin, a small mitochondrial protein, whose transcription is directly stimulated by c-Myc, is highly expressed in 80% of esophageal squamous cell carcinomas (ESCC). Suppression of Mimitin expression by RNA interference had no effect in cancerous cell lines such as human cervical carcinoma or hepatocarcinoma cell lines, but caused a decrease in cell proliferation in human glioblastoma, embryonic lung fibroblastic cells, and ESCC, suggesting Mimitin may play a special role in these types of cells. Mimitin expression is also regulated by MAPK kinases and IL-1, but not through the NF-kappa-B-related pathway. It will interact with the microtubular protein MAP1S and can affect the activities of caspase-3 and -7 in cells stimulated to develop apoptosis. Other experiments suggest that Mimitin also acts as a molecular chaperone for the assembly of the mitochondrial complex I.
Spécification

Spécification

NDUFAF2
Polyclonal
Unconjugated
NDUFAF2
B17.2 like, B17.2L, mimitin, Mimitin, mitochondrial, MMTN, NDUFA12 like protein, NDUFA12L, NDUFAF2
Rabbit
Antigen Affinity Chromatography
RUO
361894, 75597, 91942
-20°C
Liquid
Immunocytochemistry, Immunoprecipitation, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
0.13 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Q8N183
Ndufaf2
NDUFAF2 Fusion Protein Ag4853
20 μL
Primary
Human, Rat, Mouse
Antibody
IgG
Vidéos
FDS
Documents
Certificats
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