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NFKB1 Rabbit anti-Human, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Marque:  Proteintech 23576-1-AP-150UL

Informations supplémentaires : Poids : 0.00010kg

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Code produit. 16832395

  • 325.38€ / 150µL
Expédition estimée: 27-09-2022
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Description

Description

This antibody can bind p105 isoforms of NFKB1.

NF-kB is a nuclear transcription factor activated by various extra and intracellular stimuli such as cytokines, UV radiation, stress, in injury, and by bacterial and viral products. It is involved in regulation of various cellular events including cell growth, differentiation, proliferation, apoptosis and inflammation. NFKB1 (p50), a 50 kDa functional sub-unit of NF-kB, is a member of Rel protein family. It is synthesized as a p105 precursor protein and consists of an N-terminal conserved RHD-region containing nuclear localization signal, DNA-binding and dimerization domains. NFKB1 (p50) forms homodimers or heterodimerizes with p65, forming the functional NF-kB factor. NFKB1 (p50) directs the nuclear translocation of NF-kB and is instrumental in its DNA-binding. Pathological role of NF-kB has been suggested in AIDS, hematogenic cancer cell metastasis and rheumatoid arthritis.
Spécification

Spécification

NFKB1
Polyclonal
Unconjugated
NFKB1
DNA binding factor KBF1, EBP 1, KBF1, NF kappa B, NFKB p105, NFKB p50, NFKB1, NFKB1,p105, NFKB1,p105,p50, nfkb1a, p105, p50
Rabbit
Antigen Affinity Chromatography
RUO
4790
-20°C
Liquid
Western Blot, Immunohistochemistry (Paraffin), Immunofluorescence, Immunocytochemistry
0.54 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
P19838
NFKB1
NFKB1 Fusion Protein Ag20297
150 μL
Primary
Human
Antibody
IgG
Vidéos
FDS
Documents
Certificats
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