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OCRL Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Marque:  Proteintech 17695-1-AP-20UL

Informations supplémentaires : Poids : 0.00010kg

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Code produit. 16837634

  • 121.38€ / 20µL
Expédition estimée: 30-09-2022
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Description

Description

This antibody is specific to OCRL.

The inositol polyphosphate 5-phosphatases selectively remove the phosphate from the 5-position of various phosphatidylinositols, which generate second messengers in response to extracellular signals. OCRL1 is a type II 5-phosphatase that is mutated in the oculocerebrorenal syndrome of Lowe (OCRL). OCRL is a rare X-linked disorder that is characterized in part by congenital cataracts, mental retardation, muscular hypotonia and renal tubular dysfunction.OCRL1 has a high affinity for phosphatidylinositol 4,5-bisphosphate as well as inositol 1,4,5-trisphosphate and inositol 1,3,4,5-tetrakisphosphate as substrates. OCRL1 is localized to the Golgi complex and is thought to be part of the trans-Golgi network (TGN), which suggests that OCRL1 plays a role in protein sorting and trafficking within the cell.
Spécification

Spécification

OCRL
Polyclonal
Unconjugated
OCRL
INPP5F, LOCR, OCRL, OCRL1
Rabbit
Antigen Affinity Chromatography
RUO
317576, 320634, 4952
-20°C
Liquid
Immunoprecipitation, Western Blot, Immunohistochemistry (Paraffin)
0.13 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
D3ZGS3, Q01968, Q6NVF0
Ocrl
OCRL Fusion Protein Ag11900
20 μL
Primary
Mouse, Rat, Human
Antibody
IgG
Vidéos
FDS
Documents
Certificats
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