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OCRL Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Marque: Proteintech 17695-1-AP-150UL
Informations supplémentaires : Poids : 0.00010kg
Description
This antibody is specific to OCRL.
The inositol polyphosphate 5-phosphatases selectively remove the phosphate from the 5-position of various phosphatidylinositols, which generate second messengers in response to extracellular signals. OCRL1 is a type II 5-phosphatase that is mutated in the oculocerebrorenal syndrome of Lowe (OCRL). OCRL is a rare X-linked disorder that is characterized in part by congenital cataracts, mental retardation, muscular hypotonia and renal tubular dysfunction.OCRL1 has a high affinity for phosphatidylinositol 4,5-bisphosphate as well as inositol 1,4,5-trisphosphate and inositol 1,3,4,5-tetrakisphosphate as substrates. OCRL1 is localized to the Golgi complex and is thought to be part of the trans-Golgi network (TGN), which suggests that OCRL1 plays a role in protein sorting and trafficking within the cell.Spécification
OCRL | |
Polyclonal | |
Unconjugated | |
OCRL | |
INPP5F, LOCR, OCRL, OCRL1 | |
Rabbit | |
Antigen Affinity Chromatography | |
RUO | |
317576, 320634, 4952 | |
-20°C | |
Liquid |
Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot | |
0.13 mg/mL | |
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 | |
D3ZGS3, Q01968, Q6NVF0 | |
Ocrl | |
OCRL Fusion Protein Ag11900 | |
150 μL | |
Primary | |
Human, Mouse, Rat | |
Antibody | |
IgG |