missing translation for 'onlineSavingsMsg'
Learn More

PAI-1 Mouse anti-Human, Porcine, Clone: 1H4A5, Proteintech

Mouse Monoclonal Antibody

Marque:  Proteintech 66261-1-IG-150UL

Informations supplémentaires : Poids : 0.00010kg

 Afficher plus de versions de ce produit

Code produit. 16837975

  • 325.38€ / 150µL
Expédition estimée: 30-09-2022
pour voir le stock disponible 

Veuillez vous pour pouvoir commander cet article. Besoin d'un compte web? Créer le vôtre dès maintenant!


Description

Description

PAI1 (plasminogen activator inhibitor 1) belongs to serine protease inhibitor superfamily, and is the principal inhibitor of tissue-type and urokinase-type plasminogen activators (tPA and uPA). Platelets are the main source of the circulating PAI11, but it is synthesized and secreted by many tissue and cell types, including fibroblasts, smooth muscle cells, endothelial cells, hepatocytes, and inflammatory cells. Expression of PAI11 can be regulated at the transcriptional level by many factors including growth factors, cytokines, hormones, inflammatory factors, glucose or lipid metabolites, vascular tone regulating factors, chemicals, and other environmental or physical factors. PAI1 is present at increased levels in various disease states, and has been linked to an increased occurrence of thrombosis in obesity, thrombophilia and the metabolic syndrome. Defects in PAI-1 are characterized by abnormal bleeding. PAI1 mediates inhibition of fibrinolysis by inhibiting the activity of plasminogen activator, and may promote neuronal survival. Other defects in PAI1 are the cause of plasminogen activator inhibitor-1 deficiency (PAI-1 deficiency). Alternatively spliced transcript variants encoding different isoforms of PAI1 have been found.
Spécification

Spécification

PAI-1
Monoclonal
1 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
P05121, P79335
SERPINE1
PAI-1 Fusion Protein Ag22411
150 μL
Primary
Porcine, Human
Antibody
IgG1
Western Blot, Immunohistochemistry (Paraffin), Immunofluorescence, Immunocytochemistry
1H4A5
Unconjugated
SERPINE1
PAI, PAI 1, PAI1, PLANH1, Serpin E1, SERPINE1
Mouse
Protein G
RUO
396945, 5054
-20°C
Liquid
Vidéos
FDS
Documents
Certificats
Promotions

Promotions