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PAX8 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Marque:  Proteintech 10336-1-AP-150UL

Informations supplémentaires : Poids : 0.00010kg

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Code produit. 16836663

  • 399.00€ / 150µL
Expédition estimée: 15-04-2024
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Description

Description

This antibody can detect all 5 isoforms of PAX8 (31 kDa, 34 kDa, 41 kDa, 43 kDa, and 48 kDa). A 58-60 kDa form has also been reported. Proteintech's 10336-1-AP antibody has cross-reactivities with the other PAX family members.

PAX8 is a member of the paired box (PAX) family of transcription factors. Members of this gene family typically contain a paired box domain, an octapeptide, and a paired-type homeodomain. Pax8 is expressed in the developing and adult thyroid and kidney. In the thyroid, PAX8 regulates thyroglobulin, thyroidperoxidase,and NIS (sodium/iodide symporter) expression. Mutations in PAX8 have been associated with thyroid dysgenesis, thyroid follicular carcinomas and atypical follicular thyroid adenomas.
Spécification

Spécification

PAX8
Polyclonal
Unconjugated
PAX8
paired box 8, Paired box protein Pax 8, PAX8
Rabbit
Antigen Affinity Chromatography
RUO
18510, 7849, 81819
-20°C
Liquid
Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation
0.23 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
P51974, Q00288, Q06710
Pax8
PAX8 Fusion Protein Ag0306
150 μL
Primary
Human, Mouse, Rat
Antibody
IgG
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