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PICK1 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
140.00€ - 399.00€
Spécification
Antigène | PICK1 |
---|---|
Concentration | 0.13 mg/mL |
Applications | Western Blot, Immunoprecipitation, Immunohistochemistry (Paraffin), Immunofluorescence, Immunocytochemistry |
Classification | Polyclonal |
Conjugué | Unconjugated |
Code produit | Marque | Quantité | Prix | Quantité et disponibilité | |||||
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Code produit | Marque | Quantité | Prix | Quantité et disponibilité | |||||
16847733
|
Proteintech
10983-2-AP-20UL |
20 μL |
140.00€
20µL |
Expédition estimée: 17-05-2024 Connectez-vous pour voir le stock disponible |
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16837733
|
Proteintech
10983-2-AP-150UL |
150 μL |
399.00€
150µL |
Expédition estimée: 17-05-2024 Connectez-vous pour voir le stock disponible |
Veuillez vous connecter pour pouvoir commander cet article. Besoin d'un compte web? Créer le vôtre dès maintenant! | ||||
Description
PSD-95/DLG/ZO-1 (PDZ) domain-containing proteins play a central role in synaptic membrane protein localization. The protein interacting with protein kinase C (PICK1) is a synaptic PDZ domain protein that also contains a coiled-coil and acidic domain. Studies indicate that PICK1 functions as a targeting and transport protein and has been shown to interact with protein kinase C alpha (PKCalpha), AMPA-type glutamate receptors, and several other membrane receptors via its PDZ domain. The interaction of PICK1 with PKCalpha is highly dependent on the activation of the kinase. It appears that PICK1 directs the activated form of PKCalpha to membrane anchored GluR2. Once phosphorylated by PKCalpha, GluR2 is released from the synaptic anchor proteins. Once released, GluR2 is transported from the synaptic membrane in a PICK1-dependent manner.Spécification
PICK1 | |
Western Blot, Immunoprecipitation, Immunohistochemistry (Paraffin), Immunofluorescence, Immunocytochemistry | |
Unconjugated | |
Rabbit | |
Mouse, Human, Rat | |
Q62083, Q9EP80, Q9NRD5 | |
18693, 84591, 9463 | |
PICK1 Fusion Protein Ag1443 | |
Primary | |
-20°C | |
PICK1 |
0.13 mg/mL | |
Polyclonal | |
Liquid | |
RUO | |
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3 | |
PICK, PICK1, PRKCA binding protein, PRKCABP | |
Pick1 | |
IgG | |
Antigen Affinity Chromatography | |
Antibody |