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PIWIL2 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Marque: Proteintech 14209-1-AP-150UL
Informations supplémentaires : Poids : 0.00010kg
Description
The piwi gene of Drosophila belongs to a novel class of evolutionarily conserved genes (the piwi or Argonaute family). The Piwi family is required for germ-and stem-cell development in invertebrates, and two Piwi members, MIWI and MILI (Miwi like, Piwil2, Piwi-like protein 2), are essential for spermatogenesis in mouse. MIWI and MILI partner with Piwi-interacting RNAs (piRNAs) which are 26-31 nucleotides (nt) in length; clearly distinct from the 21-23 nt of microRNAs (miRNAs) or short interfering RNAs (siRNAs). A search for murine small RNAs that might program Piwi proteins for transposon suppression revealed developmentally regulated piRNA loci, some of which resemble transposon master control loci of Drosophila. MILI might be programmed by distinct piRNA populations at different stages of germ cell development, suggesting MILI plays an important role in meiotic prophase progression.Spécification
PIWIL2 | |
Polyclonal | |
Unconjugated | |
PIWIL2 | |
Cancer/testis antigen 80, CT80, HILI, mili, piwi like 2 (Drosophila), Piwi like protein 2, PIWIL1L, PIWIL2 | |
Rabbit | |
Antigen Affinity Chromatography | |
RUO | |
306011, 55124, 57746 | |
-20°C | |
Liquid |
Immunohistochemistry (Paraffin) | |
0.19 mg/mL | |
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3 | |
Q8CDG1, Q8TC59 | |
PIWIL2 | |
PIWIL2 Fusion Protein Ag5423 | |
150 μL | |
Primary | |
Human, Mouse, Rat | |
Antibody | |
IgG |