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PKN2 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Marque:  Proteintech 14608-1-AP-20UL

Informations supplémentaires : Poids : 0.00010kg

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Code produit. 16803334

  • 112.71€ / 20µL

Expédition estimée
09-03-2021

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Description

Description

PKC-related serine/threonine-protein kinase and Rho/Rac effector protein that participates in specific signal transduction responses in the cell. Plays a role in the regulation of cell cycle progression, actin cytoskeleton assembly, cell migration, cell adhesion, tumor cell invasion and transcription activation signaling processes. Phosphorylates CTTN in hyaluro-induced astrocytes and hence decreases CTTN ability to associate with filamentous actin. Phosphorylates HDAC5, therefore lead to impair HDAC5 import. Direct RhoA target required for the regulation of the maturation of primordial junctions into apical junction formation in bronchial epithelial cells. Required for G2/M phases of the cell cycle progression and abscission during cytokinesis in a ECT2-dependent manner. Stimulates FYN kinase activity that is required for establishment of skin cell-cell adhesion during keratinocytes differentiation. Regulates epithelial bladder cells speed and direction of movement during cell migration and tumor cell invasion. Inhibits Akt pro-survival-induced kinase activity. Mediates Rho protein-induced transcriptional activation via the c-fos serum response factor (SRF). Phosphorylates HCV NS5B leading to stimulation of HCV RNA replication.
Spécification

Spécification

PKN2
0.23 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
O08874, Q16513, Q8BWW9
Pak 2, PAK2, PKN2, PRK2, PRKCL2, PRO2042, Protein kinase C like 2, protein kinase N2
Rabbit
IgG
20 μL
-20°C
Primary
109333, 207122, 5586
Immunoprecipitation, Flow Cytometry, Western Blot, Immunocytochemistry, Immunofluorescence
Unconjugated
PKN2
Liquid
PKN2
PKN2 Fusion Protein Ag6164
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Rat, Human, Mouse
Vidéos
FDS
Documents