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Plastin-L Ab-1, Mouse Monoclonal Antibody,Lab Vision™ Epredia™
Provide accurate, reproducible results with the Epredia™ Plastin-L Ab-1, Mouse Monoclonal Antibody.
Marque: Epredia MS-1326-P1ABX
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Description
L-plastin is a leukocyte specific actin bundling protein from fimbrin family of proteins. It has two actin-binding domains and two EF hand type calcium-binding domains. It gets phosphorylated on the serine residue in its headpiece region in response to a variety of inflammatory stimuli. It is hypothesized that L-plastin may play a role in regulating integrin mediated adhesion in leukocytes. L-plastin is expressed in majority of human cancer cell lines derived from solid tumors. Its expression is positively upregulated by testosteronse in andrgen receptor positive prostrate and breast cancer cells through three androgen receptor binding elements located in the upstream region of the gene.Host Species: Mouse
Clone: LPL4A.1
Isotype: IgG1
Species Reactivity: Human. Does not react with Mouse. Others not known.
Epitope: Headpiece region
Immunogen: Human recombinant L-plastin protein
Molecular Weight: 62kDa
Positive Control: Human polymorphonuclear neutrophils and monocytes, MCF-7, Jurkat cells
Cellular Localization: Cytoplasmic
Recommended for:
- Western Blotting
- Immunofluorescence (Fixed in methanol or 3% paraformaldehyde)
- Immunoprecipitation (Native)
Note:
USA: RUO; Int'l: RUO
Spécification
| Plastin-L Ab-1 | |
| Monoclonal | |
| 1mg/mL | |
| Mouse | |
| 100 μL | |
| Cytoskeletal Protein | |
| Human | |
| IgG1 |
| Immunofluorescence, Immunoprecipitation, Western Blot | |
| LPL4A.1 | |
| Unconjugated | |
| Human recombinant L-plastin protein | |
| RUO | |
| Primary | |
| Concentrated |
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