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Podoplanin Rabbit anti-Human, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

140.00€ - 399.00€

Spécification

Antigène Podoplanin
Concentration 0.35 mg/mL
Applications Western Blot
Classification Polyclonal
Conjugué Unconjugated
Consulter d'autres spécifications

Produits 2
Code produit Marque Quantité Prix Quantité et disponibilité  
Code produit Marque Quantité Prix Quantité et disponibilité  
16841645
Afficher les documents Détails de la promotion
Proteintech
22099-1-AP-20UL
20 μL
140.00€
20µL
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Économisez jusqu'à 
»
Expédition estimée: 15-04-2024
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16831645
Afficher les documents Détails de la promotion
Proteintech
22099-1-AP-150UL
150 μL
399.00€
150µL
Voir les produits de remplacement
Économisez jusqu'à 
»
Expédition estimée: 15-04-2024
pour voir le stock disponible 
Veuillez vous pour pouvoir commander cet article. Besoin d'un compte web? Créer le vôtre dès maintenant!
Description

Description

Podoplanin (PDPN, T1A, gp38, Aggrus) is a mucin type-1 glycoprotein with a 40-43 kDa molecular weight. Podoplanin is expressed in many tumors and normal cells, especially lymphatic epithelial cells and follicular DCs. Podoplanin localizes in stromal cells of peripheral lymphoid tissue and thymic epithelial cells. As a regulator of the lymphatic endothelium, podoplanin probably plays a role in maintaining the unique shape of podocytes. Podoplanin appears to serve as a ligand for CLEC-2 and expression is positively correlated with tumors expressing greater invasive and metastatic potential. Podoplanin is directly involved in cell migration, aids metastases formation and tumor cell invasion of tissue. Further, it has also been determined that podoplanin expression is induced through Src activation of Cas and, recently, there are indications of podoplanin presence on Th17 cells. Initial studies below indicate the presence of podoplanin on a small but distinct population of CD4+ cells from human PBMC. Dysfunction of the podoplanin protein has been linked to diseases such as lymphangioma and subglottis neoplasm. Podoplanin has also been proposed as a marker for lung injury due to the physiological function of the protein.
Spécification

Spécification

Podoplanin
Western Blot
Unconjugated
Rabbit
Human
Q86YL7
10630
Podoplanin Fusion Protein Ag17307
Primary
-20°C
PDPN
0.35 mg/mL
Polyclonal
Liquid
RUO
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
AGGRUS, D2 40, D2 40,M2A, D240, Glycoprotein 36, GP36, Gp38, GP40, HT1A 1, M2A, OTS8, PA2.26, PA2.26 antigen, PDPN, Podoplanin, PSEC0025, T1 alpha, T1A, T1A 2
PDPN
IgG
Antigen Affinity Chromatography
Antibody
Vidéos
FDS
Documents

Documents

Product Certifications