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PRKACA Rabbit anti-Human, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Marque: Proteintech 27398-1-AP-150UL
Informations supplémentaires : Poids : 0.00010kg
Description
Protein kinase A (PKA, cAMP-dependent protein kinase) is a key element of a ubiquitous signaling pathway important in the cell cycle, cellular communication, memory formation and behavior. PKA is composed of two catalytic (PKAc; Protein Kinase A catalytic subunit) and two regulatory subunits (PKAr). Upon binding cAMP, the complex dissociates to PKAr dimer and two activated PKAc ser/thr protein kinase catalytic monomers. The released PKAc can translocate into the nucleus and exert a regulatory role in the activation of multiple nuclear hormone receptors. However, PKAc-mediated activation of tonicity-dependent gene expression is cAMP independent. Humans express three types of PKAc subunit - PKAc alpha is present in most human tissues, PKAc beta and gamma are tissue-specific, the later is found in testes.Spécification
PRKACA | |
Polyclonal | |
Unconjugated | |
PRKACA | |
PKA C alpha, PKACA, PRKACA | |
Rabbit | |
Antigen Affinity Chromatography | |
RUO | |
5566 | |
-20°C | |
Liquid |
Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot | |
0.23 mg/mL | |
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3 | |
P17612 | |
PRKACA | |
PRKACA Fusion Protein Ag26392 | |
150 μL | |
Primary | |
Human | |
Antibody | |
IgG |