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PRKACA Rabbit anti-Human, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Marque:  Proteintech 27398-1-AP-150UL

Informations supplémentaires : Poids : 0.00010kg

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Code produit. 16835605

  • 325.38€ / 150µL
Expédition estimée: 30-09-2022
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Description

Description

Protein kinase A (PKA, cAMP-dependent protein kinase) is a key element of a ubiquitous signaling pathway important in the cell cycle, cellular communication, memory formation and behavior. PKA is composed of two catalytic (PKAc; Protein Kinase A catalytic subunit) and two regulatory subunits (PKAr). Upon binding cAMP, the complex dissociates to PKAr dimer and two activated PKAc ser/thr protein kinase catalytic monomers. The released PKAc can translocate into the nucleus and exert a regulatory role in the activation of multiple nuclear hormone receptors. However, PKAc-mediated activation of tonicity-dependent gene expression is cAMP independent. Humans express three types of PKAc subunit - PKAc alpha is present in most human tissues, PKAc beta and gamma are tissue-specific, the later is found in testes.
Spécification

Spécification

PRKACA
Polyclonal
Unconjugated
PRKACA
PKA C alpha, PKACA, PRKACA
Rabbit
Antigen Affinity Chromatography
RUO
5566
-20°C
Liquid
Western Blot, Immunoprecipitation, Immunohistochemistry (Paraffin)
0.23 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
P17612
PRKACA
PRKACA Fusion Protein Ag26392
150 μL
Primary
Human
Antibody
IgG
Vidéos
FDS
Documents
Certificats
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