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RPA/p70 (Replication Protein A) Ab-2, Mouse Monoclonal Antibody,Lab Vision™ Epredia™
Provide accurate, reproducible results Epredia™ RPA/p70 (Replication Protein A) Ab-2, Mouse Monoclonal Antibody.
Marque: Epredia MS-692-P1
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Description
Replication Protein A (RPA) (also known as human single-stranded DNA binding protein, or HSSB) is involved in DNA replication, repair, and recombination. RPA from human cells is a stable heterotrimer of 70kDa, 32-34kDa, and 11-14kDa subunits (RPA70, RPA32, and RPA14 respectively). RPA is required for the SV40 large tumor antigen-catalyzed unwinding of SV40 DNA and stimulates DNA polymerase α and δ. RPA70 is composed of three domains: an N-terminal domain that is not required for ssDNA binding or SV40 replication, a central DNA-binding domain, and a C-terminal domain that is essential for subunit interactions.Host Species: Mouse
Clone: 2H10 or 70C or αSSB70C
Isotype: IgG1/κ
Species Reactivity: Human. Others not known.
Epitope: Not determined
Immunogen: Purified human RPA protein
Molecular Weight: 70kDa
Positive Control: HeLa cells
Cellular Localization: Nuclear
Recommended for:
- Immunohistochemistry (Not suitable)
- Western Blotting
- Immunoprecipitation (Native and denatured)
- Gel Supershift
Note:
USA: RUO; Int'l: RUO
Spécification
| RPA/p70 (Replication Protein A) Ab-2 | |
| Monoclonal | |
| 200μg/mL | |
| Mouse | |
| 500 μL | |
| DNA Repair | |
| Human | |
| IgG2a κ |
| Immunoprecipitation, Western Blot | |
| 2H10 or 70C or alphaSSB70C | |
| Unconjugated | |
| Purified human RPA protein | |
| RUO | |
| Primary | |
| Concentrated |
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