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RRM2B/p53R2 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Marque:  Proteintech 18005-1-AP-150UL

Informations supplémentaires : Poids : 0.00010kg

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Code produit. 16828034

  • 325.38€ / 150µL
Expédition estimée: 30-09-2022
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Description

Description

The p53 tumor-suppressor gene integrates numerous signals that control cell life and death. Several novel molecules involved in p53 signaling, including p53R2, Chk2, p53AIP1, Noxa, PIDD, and PID/MTA2, were recently discovered. p53R2 is a p53 inducible gene that contains a p53 binding sequence and encodes a subunit of the enzyme ribonucleotide reductase. p53R2 is induced by the reagents, ultraviolet and -gamma-irradiation that cause DNA damages. The product of p53R2 gene is directly involved in the p53 checkpoint for repair of damaged DNA. The isoform of the p53 family member p73 also induces p53R2 expression. p53R2 is an important target of p53 for tumor suppression.
Spécification

Spécification

RRM2B/p53R2
Polyclonal
Unconjugated
RRM2B
p53R2, RRM2B
Rabbit
Antigen Affinity Chromatography
RUO
299976, 382985, 50484
-20°C
Liquid
Western Blot
0.3 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Q6PEE3, Q7LG56
Rrm2b
RRM2B,p53R2 Fusion Protein Ag12499
150 μL
Primary
Rat, Mouse, Human
Antibody
IgG
Vidéos
FDS
Documents
Certificats
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