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STUB1 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Marque:  Proteintech 55430-1-AP-20UL

Informations supplémentaires : Poids : 0.00010kg

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Code produit. 16836895

  • 121.38€ / 20µL
Expédition estimée: 04-10-2022
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Description

Description

This antibody is specific to STUB1.

A recently identified protein, termed carboxyl terminus of hsc70-interacting protein (CHIP), has been shown to interact both with the constitutive form of hsc70 and the stress inducible form, hsp70. This novel 35 kDa cytoplasmic protein has been shown to be highly expressed in striated muscle in vivo. Additional studies have shown that this protein is expressed over a broad range of cultured tissues. Through immunoprecipitation experiments, CHIP has been shown to directly bind to the carboxyl terminus of hsc70 and hsp70 where it decreases ATPase activity and reduces overall chaperone efficiency. CHIP has also been identified as an important protein in the ubiquitin-proteasome system. CHIP contains a U-box domain and acts as an E3 ubiquitin-ligase in conjunction with hsc70 and hsp90.
Spécification

Spécification

STUB1
Polyclonal
Unconjugated
STUB1
Antigen NY CO 7, CHIP, CLL associated antigen KW 8, HSPABP2, NY CO 7, SDCCAG7, STUB1, UBOX1
Rabbit
Antigen Affinity Chromatography
RUO
10273, 287155, 56424
-20°C
Liquid
Western Blot, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)
0.36 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Q9UNE7, Q9WUD1
Stub1
Peptide
20 μL
Primary
Human, Rat, Mouse
Antibody
IgG
Vidéos
FDS
Documents
Certificats
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