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TEAD1 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Marque: Proteintech 13283-1-AP-150UL
Informations supplémentaires : Poids : 0.00010kg
Description
TEF1 (Transcriptional enhancer factor 1), a member of the TEA/ATTS domain family, is a nuclear protein that is expressed in numerous cell types and plays a role in controlling the expression of numerous genes. TEF family members have a highly conserved DNA-binding domain TEF-1 binds to GT-IIC, SphI/II and M-CAT. TEF-1 also binds to the proximal regulatory element (PRE) of transforming growth factor-alpha, a member of the EGF family that is overexpressed in many types of cancer. Furthermore, TEF-1 represses transcription in placental cells. In vitro, TEF-1 is phosphorylated by several PKC isozymes. TEF-1 is phosphorylated in vivo at serine and threonine residues. Phosphorylation of TEF-1, both in vivo and in vitro, results in a reduction in its DNA-binding capability, which suggests a potential role for TEF-1 in PKC inhibition. TEF-1 also complexes with larger tumor antigen (TAg), and may thus have a role in tumorigenesis. Dimerization of TEF-1 may be important for TEF-1 to function as a regulator of gene transcription.Spécification
TEAD1 | |
Polyclonal | |
Unconjugated | |
TEAD1 | |
AA, NTEF 1, Protein GT IIC, REF1, TCF 13, TCF13, TEA domain family member 1, TEAD 1, TEAD1, TEF 1, TEF1, Transcription factor 13 | |
Rabbit | |
Antigen Affinity Chromatography | |
RUO | |
21676, 361630, 7003 | |
-20°C | |
Liquid |
Immunoprecipitation, Western Blot | |
0.23 mg/mL | |
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 | |
P28347, P30051 | |
Tead1 | |
TEAD1 Fusion Protein Ag4082 | |
150 μL | |
Primary | |
Human, Mouse, Rat | |
Antibody | |
IgG |